Changes in the melanocortin receptors in the hypothalamus of a rat model of cancer cachexia

Synapse. 2012 Aug;66(8):747-51. doi: 10.1002/syn.21559. Epub 2012 Apr 17.

Authors

Masami Suzuki¹, Minoru Narita, Maho Ashikawa, Sadayoshi Furuta, Motohiro Matoba, Hiroki Sasaki, Kazuyoshi Yanagihara, Kiyoshi Terawaki, Tsutomu Suzuki, Yasuhito Uezono

Affiliation

¹ Division of Cancer Pathophysiology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

PMID: 22460823
DOI: 10.1002/syn.21559

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Brain-Derived Neurotrophic Factor / genetics
Brain-Derived Neurotrophic Factor / metabolism
Cachexia / etiology
Cachexia / metabolism*
Disease Models, Animal
Hypothalamus / metabolism*
Hypothalamus / physiopathology
Male
Neoplasms / complications*
Pro-Opiomelanocortin / genetics
Pro-Opiomelanocortin / metabolism
RNA, Messenger / biosynthesis
Rats
Receptor, Melanocortin, Type 3
Receptor, Melanocortin, Type 4 / genetics
Receptor, Melanocortin, Type 4 / metabolism*
Receptors, Melanocortin / genetics
Receptors, Melanocortin / metabolism*

Substances

Brain-Derived Neurotrophic Factor
RNA, Messenger
Receptor, Melanocortin, Type 3
Receptor, Melanocortin, Type 4
Receptors, Melanocortin
melanocortin 3 receptor, rat
Pro-Opiomelanocortin