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RORγt inhibitors suppress T(H)17 responses in inflammatory arthritis and inflammatory bowel disease.
de Wit J, Al-Mossawi MH, Hühn MH, Arancibia-Cárcamo CV, Doig K, Kendrick B, Gundle R, Taylor P, Mcclanahan T, Murphy E, Zhang H, Barr K, Miller JR, Hu X, Aicher TD, Morgan RW, Glick GD, Zaller D, Correll C, Powrie F, Bowness P. de Wit J, et al. J Allergy Clin Immunol. 2016 Mar;137(3):960-3. doi: 10.1016/j.jaci.2015.09.048. Epub 2015 Nov 21. J Allergy Clin Immunol. 2016. PMID: 26611672 No abstract available.
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance.
Aschenbrenner D, Quaranta M, Banerjee S, Ilott N, Jansen J, Steere B, Chen YH, Ho S, Cox K, Arancibia-Cárcamo CV, Coles M, Gaffney E, Travis SP, Denson L, Kugathasan S, Schmitz J, Powrie F, Sansom SN, Uhlig HH. Aschenbrenner D, et al. Gut. 2021 Jun;70(6):1023-1036. doi: 10.1136/gutjnl-2020-321731. Epub 2020 Oct 9. Gut. 2021. PMID: 33037057 Free PMC article.
The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.
Schulthess J, Pandey S, Capitani M, Rue-Albrecht KC, Arnold I, Franchini F, Chomka A, Ilott NE, Johnston DGW, Pires E, McCullagh J, Sansom SN, Arancibia-Cárcamo CV, Uhlig HH, Powrie F. Schulthess J, et al. Immunity. 2019 Feb 19;50(2):432-445.e7. doi: 10.1016/j.immuni.2018.12.018. Epub 2019 Jan 23. Immunity. 2019. PMID: 30683619 Free PMC article.
CD161 Defines a Functionally Distinct Subset of Pro-Inflammatory Natural Killer Cells.
Kurioka A, Cosgrove C, Simoni Y, van Wilgenburg B, Geremia A, Björkander S, Sverremark-Ekström E, Thurnheer C, Günthard HF, Khanna N; Swiss HIV Cohort Study; Oxford IBD Cohort Investigators; Walker LJ, Arancibia-Cárcamo CV, Newell EW, Willberg CB, Klenerman P. Kurioka A, et al. Front Immunol. 2018 Apr 9;9:486. doi: 10.3389/fimmu.2018.00486. eCollection 2018. Front Immunol. 2018. PMID: 29686665 Free PMC article.
TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions.
Leng T, Akther HD, Hackstein CP, Powell K, King T, Friedrich M, Christoforidou Z, McCuaig S, Neyazi M, Arancibia-Cárcamo CV, Hagel J, Powrie F; Oxford IBD Investigators; Peres RS, Millar V, Ebner D, Lamichhane R, Ussher J, Hinks TSC, Marchi E, Willberg C, Klenerman P. Leng T, et al. Cell Rep. 2019 Sep 17;28(12):3077-3091.e5. doi: 10.1016/j.celrep.2019.08.050. Cell Rep. 2019. PMID: 31533032 Free PMC article.
38 results