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Page 1
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses.
Rodríguez-Ubreva J, Arutyunyan A, Bonder MJ, Del Pino-Molina L, Clark SJ, de la Calle-Fabregat C, Garcia-Alonso L, Handfield LF, Ciudad L, Andrés-León E, Krueger F, Català-Moll F, Rodríguez-Cortez VC, Polanski K, Mamanova L, van Dongen S, Kiselev VY, Martínez-Saavedra MT, Heyn H, Martín J, Warnatz K, López-Granados E, Rodríguez-Gallego C, Stegle O, Kelsey G, Vento-Tormo R, Ballestar E. Rodríguez-Ubreva J, et al. Nat Commun. 2022 Apr 1;13(1):1779. doi: 10.1038/s41467-022-29450-x. Nat Commun. 2022. PMID: 35365635 Free PMC article.
Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci.
Li T, Ortiz-Fernández L, Andrés-León E, Ciudad L, Javierre BM, López-Isac E, Guillén-Del-Castillo A, Simeón-Aznar CP, Ballestar E, Martin J. Li T, et al. Genome Med. 2020 Sep 25;12(1):81. doi: 10.1186/s13073-020-00779-6. Genome Med. 2020. PMID: 32977850 Free PMC article.
Methylome and transcriptome profiling of giant cell arteritis monocytes reveals novel pathways involved in disease pathogenesis and molecular response to glucocorticoids.
Estupiñán-Moreno E, Ortiz-Fernández L, Li T, Hernández-Rodríguez J, Ciudad L, Andrés-León E, Terron-Camero LC, Prieto-González S, Espígol-Frigolé G, Cid MC, Márquez A, Ballestar E, Martín J. Estupiñán-Moreno E, et al. Ann Rheum Dis. 2022 Aug 11;81(9):1290-1300. doi: 10.1136/annrheumdis-2022-222156. Ann Rheum Dis. 2022. PMID: 35705375 Free PMC article.
Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection.
Barmada A, Handfield LF, Godoy-Tena G, de la Calle-Fabregat C, Ciudad L, Arutyunyan A, Andrés-León E, Hoo R, Porter T, Oszlanczi A, Richardson L, Calero-Nieto FJ, Wilson NK, Marchese D, Sancho-Serra C, Carrillo J, Presas-Rodríguez S, Ramo-Tello C, Ruiz-Sanmartin A, Ferrer R, Ruiz-Rodriguez JC, Martínez-Gallo M, Munera-Campos M, Carrascosa JM, Göttgens B, Heyn H, Prigmore E, Casafont-Solé I, Solanich X, Sánchez-Cerrillo I, González-Álvaro I, Raimondo MG, Ramming A, Martin J, Martínez-Cáceres E, Ballestar E, Vento-Tormo R, Rodríguez-Ubreva J. Barmada A, et al. Among authors: andres leon e. Eur J Immunol. 2024 Jan;54(1):e2350633. doi: 10.1002/eji.202350633. Epub 2023 Oct 20. Eur J Immunol. 2024. PMID: 37799110
GWAS loci associated with Chagas cardiomyopathy influences DNA methylation levels.
Casares-Marfil D, Kerick M, Andrés-León E, Bosch-Nicolau P, Molina I; Chagas Genetics CYTED Network; Martin J, Acosta-Herrera M. Casares-Marfil D, et al. PLoS Negl Trop Dis. 2021 Oct 29;15(10):e0009874. doi: 10.1371/journal.pntd.0009874. eCollection 2021 Oct. PLoS Negl Trop Dis. 2021. PMID: 34714828 Free PMC article.
Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1.
García-Domínguez DJ, Hajji N, López-Alemany R, Sánchez-Molina S, Figuerola-Bou E, Morón Civanto FJ, Rello-Varona S, Andrés-León E, Benito A, Keun HC, Mora J, Tirado ÓM, de Álava E, Hontecillas-Prieto L. García-Domínguez DJ, et al. Oncogene. 2022 Apr;41(18):2638-2650. doi: 10.1038/s41388-022-02279-w. Epub 2022 Mar 30. Oncogene. 2022. PMID: 35354905 Free PMC article.
The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.
Lynch CJ, Bernad R, Calvo I, Nóbrega-Pereira S, Ruiz S, Ibarz N, Martinez-Val A, Graña-Castro O, Gómez-López G, Andrés-León E, Espinosa Angarica V, Del Sol A, Ortega S, Fernandez-Capetillo O, Rojo E, Munoz J, Serrano M. Lynch CJ, et al. Cell Rep. 2018 Jan 9;22(2):396-410. doi: 10.1016/j.celrep.2017.12.062. Cell Rep. 2018. PMID: 29320736 Free PMC article.
Mapping the entire functionally active endometrial microbiota.
Sola-Leyva A, Andrés-León E, Molina NM, Terron-Camero LC, Plaza-Díaz J, Sáez-Lara MJ, Gonzalvo MC, Sánchez R, Ruíz S, Martínez L, Altmäe S. Sola-Leyva A, et al. Hum Reprod. 2021 Mar 18;36(4):1021-1031. doi: 10.1093/humrep/deaa372. Hum Reprod. 2021. PMID: 33598714
55 results