Pre-validation study of spectrophotometric direct peptide reactivity assay (Spectro-DPRA) as a modified in chemico skin sensitization test method.
Seo JA, Cho SA, Park CE, Seo DH, Choi M, An S, Kim BH.
Seo JA, et al. Among authors: an s.
Toxicol Res. 2022 Jun 4;38(4):531-544. doi: 10.1007/s43188-022-00130-8. eCollection 2022 Oct.
Toxicol Res. 2022.
PMID: 36277359
Free PMC article.
Direct peptide reactivity assay (DPRA) has been adopted by the OECD as an alternative method to evaluate skin sensitization by assessing a substance's reaction to two model peptides. ...The reproducibility among the three laboratories was as high as 86.7%; the accur …
Direct peptide reactivity assay (DPRA) has been adopted by the OECD as an alternative method to evaluate skin sensitization by assess …