Propofol inhibits carbachol-induced chloride secretion by directly targeting the basolateral K+ channel in rat ileum epithelium.
Tang SH, Wang HY, Sun H, An N, Xiao L, Sun Q, Zhao DB.
Tang SH, et al. Among authors: an n.
Neurogastroenterol Motil. 2017 Feb;29(2). doi: 10.1111/nmo.12934. Epub 2016 Aug 30.
Neurogastroenterol Motil. 2017.
PMID: 27578144
Free article.
The inhibitory effect of propofol was only evident after application to the serosal side. Pretreatment with tetrodotoxin (TTX, 0.3 mumol/L, n=5) had no effect on propofol-induced inhibitory effect, whereas serosal application of K(+) channel inhibitor, glibenclamide, but n …
The inhibitory effect of propofol was only evident after application to the serosal side. Pretreatment with tetrodotoxin (TTX, 0.3 mumol/L, …