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Acid ceramidase confers radioresistance to glioblastoma cells.
Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP. Doan NB, et al. Among authors: al gizawiy mm. Oncol Rep. 2017 Oct;38(4):1932-1940. doi: 10.3892/or.2017.5855. Epub 2017 Jul 28. Oncol Rep. 2017. PMID: 28765947 Free PMC article.
Comprehensive characterization of glioblastoma tumor tissues for biomarker identification using mass spectrometry-based label-free quantitative proteomics.
Heroux MS, Chesnik MA, Halligan BD, Al-Gizawiy M, Connelly JM, Mueller WM, Rand SD, Cochran EJ, LaViolette PS, Malkin MG, Schmainda KM, Mirza SP. Heroux MS, et al. Physiol Genomics. 2014 Jul 1;46(13):467-81. doi: 10.1152/physiolgenomics.00034.2014. Epub 2014 May 6. Physiol Genomics. 2014. PMID: 24803679 Free PMC article.
Acid ceramidase is a novel drug target for pediatric brain tumors.
Doan NB, Nguyen HS, Montoure A, Al-Gizawiy MM, Mueller WM, Kurpad S, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP. Doan NB, et al. Among authors: al gizawiy mm. Oncotarget. 2017 Apr 11;8(15):24753-24761. doi: 10.18632/oncotarget.15800. Oncotarget. 2017. PMID: 28445970 Free PMC article.
Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency.
Doan NB, Alhajala H, Al-Gizawiy MM, Mueller WM, Rand SD, Connelly JM, Cochran EJ, Chitambar CR, Clark P, Kuo J, Schmainda KM, Mirza SP. Doan NB, et al. Among authors: al gizawiy mm. Oncotarget. 2017 Nov 7;8(68):112662-112674. doi: 10.18632/oncotarget.22637. eCollection 2017 Dec 22. Oncotarget. 2017. PMID: 29348854 Free PMC article.
Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase.
Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM. Chitambar CR, et al. Among authors: al gizawiy mm. Mol Cancer Ther. 2018 Jun;17(6):1240-1250. doi: 10.1158/1535-7163.MCT-17-1009. Epub 2018 Mar 28. Mol Cancer Ther. 2018. PMID: 29592883 Free PMC article.
Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model.
Doan NB, Nguyen HS, Alhajala HS, Jaber B, Al-Gizawiy MM, Ahn EE, Mueller WM, Chitambar CR, Mirza SP, Schmainda KM. Doan NB, et al. Among authors: al gizawiy mm. Oncotarget. 2018 May 4;9(34):23532-23542. doi: 10.18632/oncotarget.25247. eCollection 2018 May 4. Oncotarget. 2018. PMID: 29805753 Free PMC article.
Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes.
Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Erin Ahn EY, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB. Alhajala HS, et al. Among authors: al gizawiy mm. Oncotarget. 2018 Sep 25;9(75):34122-34131. doi: 10.18632/oncotarget.26137. eCollection 2018 Sep 25. Oncotarget. 2018. PMID: 30344926 Free PMC article.
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