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Tumor suppression by small molecule inhibitors of translation initiation.
Chen L, Aktas BH, Wang Y, He X, Sahoo R, Zhang N, Denoyelle S, Kabha E, Yang H, Freedman RY, Supko JG, Chorev M, Wagner G, Halperin JA. Chen L, et al. Among authors: aktas bh. Oncotarget. 2012 Aug;3(8):869-81. doi: 10.18632/oncotarget.598. Oncotarget. 2012. PMID: 22935625 Free PMC article.
Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Papadopoulos E, Jenni S, Kabha E, Takrouri KJ, Yi T, Salvi N, Luna RE, Gavathiotis E, Mahalingam P, Arthanari H, Rodriguez-Mias R, Yefidoff-Freedman R, Aktas BH, Chorev M, Halperin JA, Wagner G. Papadopoulos E, et al. Among authors: aktas bh. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3187-95. doi: 10.1073/pnas.1410250111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049413 Free PMC article.
34 results