Akritopoulou-Zanze I - Search Results

1

Isocyanide-based multicomponent reactions in drug discovery.

Akritopoulou-Zanze I. Akritopoulou-Zanze I. Curr Opin Chem Biol. 2008 Jun;12(3):324-31. doi: 10.1016/j.cbpa.2008.02.004. Epub 2008 Mar 14. Curr Opin Chem Biol. 2008. PMID: 18312861 Review.

2

The identification of new protein kinase inhibitors as targets in modern drug discovery.

Akritopoulou-Zanze I. Akritopoulou-Zanze I. IDrugs. 2006 Jul;9(7):481-7. IDrugs. 2006. PMID: 16821161 Review.

3

Scaffold oriented synthesis. Part 4: design, synthesis and biological evaluation of novel 5-substituted indazoles as potent and selective kinase inhibitors employing heterocycle forming and multicomponent reactions.

Akritopoulou-Zanze I, Wakefield BD, Gasiecki A, Kalvin D, Johnson EF, Kovar P, Djuric SW. Akritopoulou-Zanze I, et al. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1480-3. doi: 10.1016/j.bmcl.2011.01.001. Epub 2011 Jan 11. Bioorg Med Chem Lett. 2011. PMID: 21288717

4

When analoging is not enough: scaffold discovery in medicinal chemistry.

Zhao H, Akritopoulou-Zanze I. Zhao H, et al. Among authors: akritopoulou zanze i. Expert Opin Drug Discov. 2010 Feb;5(2):123-34. doi: 10.1517/17460440903584874. Epub 2010 Jan 9. Expert Opin Drug Discov. 2010. PMID: 22822912

5

Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists.

Akritopoulou-Zanze I, Patel JR, Hartandi K, Brenneman J, Winn M, Pratt JK, Grynfarb M, Goos-Nisson A, Von Geldern TW, Kym PR. Akritopoulou-Zanze I, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2079-82. doi: 10.1016/j.bmcl.2004.02.048. Bioorg Med Chem Lett. 2004. PMID: 15080982

6

Scaffold oriented synthesis. Part 1: Design, preparation, and biological evaluation of thienopyrazoles as kinase inhibitors.

Akritopoulou-Zanze I, Darczak D, Sarris K, Phelan KM, Huth JR, Song D, Johnson EF, Jia Y, Djuric SW. Akritopoulou-Zanze I, et al. Bioorg Med Chem Lett. 2006 Jan 1;16(1):96-9. doi: 10.1016/j.bmcl.2005.09.042. Epub 2005 Oct 10. Bioorg Med Chem Lett. 2006. PMID: 16216502

7

The use of three-dimensional shape and electrostatic similarity searching in the identification of a melanin-concentrating hormone receptor 1 antagonist.

Muchmore SW, Souers AJ, Akritopoulou-Zanze I. Muchmore SW, et al. Chem Biol Drug Des. 2006 Feb;67(2):174-6. doi: 10.1111/j.1747-0285.2006.00341.x. Chem Biol Drug Des. 2006. PMID: 16492165

8

Synthesis and biological evaluation of 5-substituted 1,4-dihydroindeno[1,2-c]pyrazoles as multitargeted receptor tyrosine kinase inhibitors.

Akritopoulou-Zanze I, Albert DH, Bousquet PF, Cunha GA, Harris CM, Moskey M, Dinges J, Stewart KD, Sowin TJ. Akritopoulou-Zanze I, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3136-40. doi: 10.1016/j.bmcl.2007.03.031. Epub 2007 Mar 15. Bioorg Med Chem Lett. 2007. PMID: 17391959

9

Topography-biased compound library design: the shape of things to come?

Akritopoulou-Zanze I, Metz JT, Djuric SW. Akritopoulou-Zanze I, et al. Drug Discov Today. 2007 Nov;12(21-22):948-52. doi: 10.1016/j.drudis.2007.08.017. Epub 2007 Oct 17. Drug Discov Today. 2007. PMID: 17993413 Review.

10

1,4-Dihydroindeno[1,2-c]pyrazoles as novel multitargeted receptor tyrosine kinase inhibitors.

Dinges J, Ashworth KL, Akritopoulou-Zanze I, Arnold LD, Baumeister SA, Bousquet PF, Cunha GA, Davidsen SK, Djuric SW, Gracias VJ, Michaelides MR, Rafferty P, Sowin TJ, Stewart KD, Xia Z, Zhang HQ. Dinges J, et al. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4266-71. doi: 10.1016/j.bmcl.2006.05.066. Epub 2006 Jun 12. Bioorg Med Chem Lett. 2006. PMID: 16759855

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