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Page 1
Emerging mechanisms of glutathione-dependent chemistry in biology and disease.
Janssen-Heininger YM, Nolin JD, Hoffman SM, van der Velden JL, Tully JE, Lahue KG, Abdalla ST, Chapman DG, Reynaert NL, van der Vliet A, Anathy V. Janssen-Heininger YM, et al. Among authors: abdalla st. J Cell Biochem. 2013 Sep;114(9):1962-8. doi: 10.1002/jcb.24551. J Cell Biochem. 2013. PMID: 23554102 Free PMC article. Review.
Reducing protein oxidation reverses lung fibrosis.
Anathy V, Lahue KG, Chapman DG, Chia SB, Casey DT, Aboushousha R, van der Velden JLJ, Elko E, Hoffman SM, McMillan DH, Jones JT, Nolin JD, Abdalla S, Schneider R, Seward DJ, Roberson EC, Liptak MD, Cousins ME, Butnor KJ, Taatjes DJ, Budd RC, Irvin CG, Ho YS, Hakem R, Brown KK, Matsui R, Bachschmid MM, Gomez JL, Kaminski N, van der Vliet A, Janssen-Heininger YMW. Anathy V, et al. Nat Med. 2018 Aug;24(8):1128-1135. doi: 10.1038/s41591-018-0090-y. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988126 Free PMC article.
Ablation of the Thiol Transferase Glutaredoxin-1 Augments Protein S-Glutathionylation and Modulates Type 2 Inflammatory Responses and IL-17 in a House Dust Mite Model of Allergic Airway Disease in Mice.
Hoffman SM, Nolin JD, Jones JT, Lahue KG, Chapman DG, Aliyeva M, Daphtary N, Lundblad LK, Abdalla S, Ather JL, Ho YS, Irvin CG, Anathy V, Wouters EF, Poynter ME, Janssen-Heininger YM. Hoffman SM, et al. Ann Am Thorac Soc. 2016 Mar;13 Suppl 1(Suppl 1):S97. doi: 10.1513/AnnalsATS.201510-656MG. Ann Am Thorac Soc. 2016. PMID: 27027965 Free PMC article.
Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice.
Hoffman SM, Qian X, Nolin JD, Chapman DG, Chia SB, Lahue KG, Schneider R, Ather JL, Randall MJ, McMillan DH, Jones JT, Taatjes DJ, Aliyeva M, Daphtary N, Abdalla S, Lundblad LK, Ho YS, Anathy V, Irvin CG, Wouters EF, Reynaert NL, Dixon AE, van der Vliet A, Poynter ME, Janssen-Heininger YM. Hoffman SM, et al. Am J Respir Cell Mol Biol. 2016 Sep;55(3):377-86. doi: 10.1165/rcmb.2015-0401OC. Am J Respir Cell Mol Biol. 2016. PMID: 27035878 Free PMC article.
Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π.
McMillan DH, van der Velden JL, Lahue KG, Qian X, Schneider RW, Iberg MS, Nolin JD, Abdalla S, Casey DT, Tew KD, Townsend DM, Henderson CJ, Wolf CR, Butnor KJ, Taatjes DJ, Budd RC, Irvin CG, van der Vliet A, Flemer S, Anathy V, Janssen-Heininger YM. McMillan DH, et al. JCI Insight. 2016 Jun 2;1(8):e85717. doi: 10.1172/jci.insight.85717. JCI Insight. 2016. PMID: 27358914 Free PMC article.
TGF-β1-induced deposition of provisional extracellular matrix by tracheal basal cells promotes epithelial-to-mesenchymal transition in a c-Jun NH2-terminal kinase-1-dependent manner.
van der Velden JL, Wagner DE, Lahue KG, Abdalla ST, Lam YW, Weiss DJ, Janssen-Heininger YMW. van der Velden JL, et al. Among authors: abdalla st. Am J Physiol Lung Cell Mol Physiol. 2018 Jun 1;314(6):L984-L997. doi: 10.1152/ajplung.00053.2017. Epub 2018 Feb 22. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29469614 Free PMC article.
JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers.
van der Velden JL, Ye Y, Nolin JD, Hoffman SM, Chapman DG, Lahue KG, Abdalla S, Chen P, Liu Y, Bennett B, Khalil N, Sutherland D, Smith W, Horan G, Assaf M, Horowitz Z, Chopra R, Stevens RM, Palmisano M, Janssen-Heininger YM, Schafer PH. van der Velden JL, et al. Clin Transl Med. 2016 Dec;5(1):36. doi: 10.1186/s40169-016-0117-2. Epub 2016 Sep 2. Clin Transl Med. 2016. PMID: 27590145 Free PMC article.