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2004 1
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A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A. Skarnes WC, et al. Nature. 2011 Jun 15;474(7351):337-42. doi: 10.1038/nature10163. Nature. 2011. PMID: 21677750 Free PMC article.
Dual RMCE for efficient re-engineering of mouse mutant alleles.
Osterwalder M, Galli A, Rosen B, Skarnes WC, Zeller R, Lopez-Rios J. Osterwalder M, et al. Nat Methods. 2010 Nov;7(11):893-5. doi: 10.1038/nmeth.1521. Epub 2010 Oct 17. Nat Methods. 2010. PMID: 20953177 Free PMC article.
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.
Landeira D, Sauer S, Poot R, Dvorkina M, Mazzarella L, Jørgensen HF, Pereira CF, Leleu M, Piccolo FM, Spivakov M, Brookes E, Pombo A, Fisher C, Skarnes WC, Snoek T, Bezstarosti K, Demmers J, Klose RJ, Casanova M, Tavares L, Brockdorff N, Merkenschlager M, Fisher AG. Landeira D, et al. Nat Cell Biol. 2010 Jun;12(6):618-24. doi: 10.1038/ncb2065. Epub 2010 May 16. Nat Cell Biol. 2010. PMID: 20473294 Free PMC article.
Agouti C57BL/6N embryonic stem cells for mouse genetic resources.
Pettitt SJ, Liang Q, Rairdan XY, Moran JL, Prosser HM, Beier DR, Lloyd KC, Bradley A, Skarnes WC. Pettitt SJ, et al. Nat Methods. 2009 Jul;6(7):493-5. doi: 10.1038/nmeth.1342. Epub 2009 Jun 14. Nat Methods. 2009. PMID: 19525957 Free PMC article.
The European dimension for the mouse genome mutagenesis program.
Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, de Angelis MH, Jackson I, Kioussis D, Kollias G, Lathrop M, Lendahl U, Malumbres M, von Melchner H, Müller W, Partanen J, Ricciardi-Castagnoli P, Rigby P, Rosen B, Rosenthal N, Skarnes B, Stewart AF, Thornton J, Tocchini-Valentini G, Wagner E, Wahli W, Wurst W. Auwerx J, et al. Nat Genet. 2004 Sep;36(9):925-7. doi: 10.1038/ng0904-925. Nat Genet. 2004. PMID: 15340424 Free PMC article.