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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2017 8
2018 42
2019 93
2020 113
2021 124
2022 192
2023 213
2024 141

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832 results

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Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer.
Zhang H, Qin C, An C, Zheng X, Wen S, Chen W, Liu X, Lv Z, Yang P, Xu W, Gao W, Wu Y. Zhang H, et al. Mol Cancer. 2021 Oct 1;20(1):126. doi: 10.1186/s12943-021-01431-6. Mol Cancer. 2021. PMID: 34598686 Free PMC article. Review.
The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna for the development of the Clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease9 (CRISPR/Cas9) gene editing technology that provided new tools for pr …
The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna for the development of the Clustered regu …
CircRNA-CREIT inhibits stress granule assembly and overcomes doxorubicin resistance in TNBC by destabilizing PKR.
Wang X, Chen T, Li C, Li W, Zhou X, Li Y, Luo D, Zhang N, Chen B, Wang L, Zhao W, Fu S, Yang Q. Wang X, et al. J Hematol Oncol. 2022 Aug 29;15(1):122. doi: 10.1186/s13045-022-01345-w. J Hematol Oncol. 2022. PMID: 36038948 Free PMC article.
Further investigations revealed that a combination of the SG inhibitor ISRIB and doxorubicin synergistically inhibited TNBC tumor growth. Besides, circRNA-CREIT could be packaged into exosomes and disseminate doxorubicin sensitivity among TNBC cells. ...
Further investigations revealed that a combination of the SG inhibitor ISRIB and doxorubicin synergistically inhibited TNBC tumor growth …
SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis.
Feng L, Zhao K, Sun L, Yin X, Zhang J, Liu C, Li B. Feng L, et al. J Transl Med. 2021 Aug 26;19(1):367. doi: 10.1186/s12967-021-03042-7. J Transl Med. 2021. PMID: 34446045 Free PMC article.
BACKGROUND: Solute carrier family 7 member 11(SLC7A11) is a component of cysteine/glutamate transporter, which plays a key role in tumor growth; however, its underlying effect on radiosensitivity in esophageal squamous cell carcinoma (ESCC) remains unclear. ...
BACKGROUND: Solute carrier family 7 member 11(SLC7A11) is a component of cysteine/glutamate transporter, which plays a key role in tumor …
Analysis of Current Situation, Demand and Development Trend of Casting Grinding Technology.
Liang H, Qiao J. Liang H, et al. Micromachines (Basel). 2022 Sep 22;13(10):1577. doi: 10.3390/mi13101577. Micromachines (Basel). 2022. PMID: 36295930 Free PMC article. Review.
The grinding process has a long history. This paper focus on its development from a human-operated, mechanical job, to an automatic grinding task based on compliant control theory. ...
The grinding process has a long history. This paper focus on its development from a human-operated, mechanical job, to an automatic g …
Progress in research and application development of surface display technology using Bacillus subtilis spores.
Lin P, Yuan H, Du J, Liu K, Liu H, Wang T. Lin P, et al. Appl Microbiol Biotechnol. 2020 Mar;104(6):2319-2331. doi: 10.1007/s00253-020-10348-x. Epub 2020 Jan 27. Appl Microbiol Biotechnol. 2020. PMID: 31989224 Free PMC article. Review.
We have mainly focused on the regulation of spore coat protein expression, display and application of exogenous proteins, and identification of developing research areas of spore surface display technology....
We have mainly focused on the regulation of spore coat protein expression, display and application of exogenous proteins, and identification …
A method of genetic transformation and gene editing of succulents without tissue culture.
Lu J, Li S, Deng S, Wang M, Wu Y, Li M, Dong J, Lu S, Su C, Li G, Lang Z, Zhu JK. Lu J, et al. Plant Biotechnol J. 2024 Feb 29. doi: 10.1111/pbi.14318. Online ahead of print. Plant Biotechnol J. 2024. PMID: 38425137 Free article.
However, only a handful of succulent species can be genetically transformed, making it difficult to improve these plants through genetic engineering. In this study, we adapted the recently developed cut-dip-budding (CDB) gene delivery system to transform three previously r …
However, only a handful of succulent species can be genetically transformed, making it difficult to improve these plants through genetic eng …
Multi-modality artificial intelligence in digital pathology.
Qiao Y, Zhao L, Luo C, Luo Y, Wu Y, Li S, Bu D, Zhao Y. Qiao Y, et al. Brief Bioinform. 2022 Nov 19;23(6):bbac367. doi: 10.1093/bib/bbac367. Brief Bioinform. 2022. PMID: 36124675 Free PMC article. Review.
Extensive research has shown that AI algorithms can produce more up-to-date and standardized conclusions for whole slide images. In conjunction with the development of high-throughput sequencing technologies, algorithms can integrate and analyze data from multiple modaliti …
Extensive research has shown that AI algorithms can produce more up-to-date and standardized conclusions for whole slide images. In conjunct …
Research Progress and Development Demand of Nanocellulose Reinforced Polymer Composites.
Shen R, Xue S, Xu Y, Liu Q, Feng Z, Ren H, Zhai H, Kong F. Shen R, et al. Polymers (Basel). 2020 Sep 17;12(9):2113. doi: 10.3390/polym12092113. Polymers (Basel). 2020. PMID: 32957464 Free PMC article. Review.
Furthermore, the influence of various factors on the properties of nanocellulose reinforced polymer composites are discussed in combination with analyses and comparisons of specific research results in related fields. Finally, research focus and development directions for …
Furthermore, the influence of various factors on the properties of nanocellulose reinforced polymer composites are discussed in combination …
hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma.
Xu L, Ma X, Zhang X, Zhang C, Zhang Y, Gong S, Wu N, Zhang P, Feng X, Guo J, Zhao M, Ren Z, Zhang P. Xu L, et al. Mol Cancer. 2023 Dec 4;22(1):195. doi: 10.1186/s12943-023-01887-8. Mol Cancer. 2023. PMID: 38044421 Free PMC article.
BACKGROUND: Circular RNAs (circRNAs) play important roles in the occurrence and development of cancer and chemoresistance. DNA damage repair contributes to the proliferation of cancer cells and resistance to chemotherapy-induced apoptosis. ...Xenograft model and IHC experi …
BACKGROUND: Circular RNAs (circRNAs) play important roles in the occurrence and development of cancer and chemoresistance. DNA damage …
832 results