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2012 2
2014 2
2015 1
2016 1
2017 2
2018 1
2019 1
2024 0

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Page 1
Genetics of Amyotrophic Lateral Sclerosis.
Ghasemi M, Brown RH Jr. Ghasemi M, et al. Cold Spring Harb Perspect Med. 2018 May 1;8(5):a024125. doi: 10.1101/cshperspect.a024125. Cold Spring Harb Perspect Med. 2018. PMID: 28270533 Free PMC article. Review.
Nucleic Acid Therapeutics for Neurological Diseases.
Watts JK, Brown RH, Khvorova A. Watts JK, et al. Neurotherapeutics. 2019 Apr;16(2):245-247. doi: 10.1007/s13311-019-00736-1. Neurotherapeutics. 2019. PMID: 31037650 Free PMC article. No abstract available.
A high-throughput screen to identify inhibitors of SOD1 transcription.
Wright PD, Wightman N, Huang M, Weiss A, Sapp PC, Cuny GD, Ivinson AJ, Glicksman MA, Ferrante RJ, Matson W, Matson S, Brown RH Jr. Wright PD, et al. Front Biosci (Elite Ed). 2012 Jun 1;4(8):2701-8. doi: 10.2741/e584. Front Biosci (Elite Ed). 2012. PMID: 22652679 Free PMC article.
A loss of FUS/TLS function leads to impaired cellular proliferation.
Ward CL, Boggio KJ, Johnson BN, Boyd JB, Douthwright S, Shaffer SA, Landers JE, Glicksman MA, Bosco DA. Ward CL, et al. Cell Death Dis. 2014 Dec 11;5(12):e1572. doi: 10.1038/cddis.2014.508. Cell Death Dis. 2014. PMID: 25501833 Free PMC article.
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans.
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, Peeters E, Philips T, Goris A, Dubois B, Andersen PM, Al-Chalabi A, Thijs V, Turnley AM, van Vught PW, Veldink JH, Hardiman O, Van Den Bosch L, Gonzalez-Perez P, Van Damme P, Brown RH Jr, van den Berg LH, Robberecht W. Van Hoecke A, et al. Nat Med. 2012 Sep;18(9):1418-22. doi: 10.1038/nm.2901. Nat Med. 2012. PMID: 22922411
Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease.
Fil D, DeLoach A, Yadav S, Alkam D, MacNicol M, Singh A, Compadre CM, Goellner JJ, O'Brien CA, Fahmi T, Basnakian AG, Calingasan NY, Klessner JL, Beal FM, Peters OM, Metterville J, Brown RH Jr, Ling KKY, Rigo F, Ozdinler PH, Kiaei M. Fil D, et al. Hum Mol Genet. 2017 Feb 15;26(4):686-701. doi: 10.1093/hmg/ddw429. Hum Mol Genet. 2017. PMID: 28040732 Free PMC article.
Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Peters OM, Cabrera GT, Tran H, Gendron TF, McKeon JE, Metterville J, Weiss A, Wightman N, Salameh J, Kim J, Sun H, Boylan KB, Dickson D, Kennedy Z, Lin Z, Zhang YJ, Daughrity L, Jung C, Gao FB, Sapp PC, Horvitz HR, Bosco DA, Brown SP, de Jong P, Petrucelli L, Mueller C, Brown RH Jr. Peters OM, et al. Neuron. 2015 Dec 2;88(5):902-909. doi: 10.1016/j.neuron.2015.11.018. Neuron. 2015. PMID: 26637797 Free PMC article.