RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST.
Chung MH, Aimaier R, Yu Q, Li H, Li Y, Wei C, Gu Y, Wang W, Guo Z, Long M, Li Q, Wang Z.
Chung MH, et al.
Cell Oncol (Dordr). 2023 Oct;46(5):1399-1413. doi: 10.1007/s13402-023-00819-4. Epub 2023 Apr 22.
Cell Oncol (Dordr). 2023.
PMID: 37086345
We detected RRM2 expression by immunochemical staining in an MPNST tissue microarray, and assessed the clinical and prognostic significance of RRM2 in an MPNST cohort. RRM2 knockdown and the RRM2 inhibitor Triapine were used to assess cell proliferation and apoptosis in NF …
We detected RRM2 expression by immunochemical staining in an MPNST tissue microarray, and assessed the clinical and prognostic signif …