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Advances in cerebral perfusion imaging techniques in acute ischemic stroke.
J Clin Ultrasound. 2022 Oct;50(8):1202-1211. doi: 10.1002/jcu.23277.
J Clin Ultrasound. 2022.
PMID: 36218215
Review.
In Vitro and In Silico Studies of Human Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) Inhibition by Stereoisomeric Forms of Lipophilic Nucleosides: The Role of Carbohydrate Stereochemistry in Ligand-Enzyme Interactions.
Dyrkheeva NS, Chernyshova IA, Ivanov GA, Porozov YB, Zenchenko AA, Oslovsky VE, Zakharenko AL, Nasyrova DI, Likhatskaya GN, Mikhailov SN, Lavrik OI, Drenichev MS.
Dyrkheeva NS, et al.
Molecules. 2022 Apr 9;27(8):2433. doi: 10.3390/molecules27082433.
Molecules. 2022.
PMID: 35458631
Free PMC article.
It was shown that D-lipophilic nucleoside derivatives manifested higher inhibition activity than their L-analogs, and configuration of the carbohydrate moiety can influence the mechanism of Tdp1 inhibition....
It was shown that D-lipophilic nucleoside derivatives manifested higher inhibition activity than their L-analogs, and configuration o …
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