Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver.
Krupenko NI, Sharma J, Pediaditakis P, Fekry B, Helke KL, Du X, Sumner S, Krupenko SA.
Krupenko NI, et al.
Sci Rep. 2019 Oct 17;9(1):14937. doi: 10.1038/s41598-019-51397-1.
Sci Rep. 2019.
PMID: 31624291
Free PMC article.
This reaction might have a regulatory function towards reduced folate pools, de novo purine biosynthesis, and the flux of folate-bound methyl groups. To understand the role of the enzyme in cellular metabolism, Aldh1l1(-/-) mice were generated using an ES cell clone (C57BL …
This reaction might have a regulatory function towards reduced folate pools, de novo purine biosynthesis, and the flux of folate-boun …