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1979 1
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2001 1
2006 3
2008 5
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2011 3
2012 9
2013 6
2014 8
2015 8
2016 7
2017 18
2018 18
2019 38
2020 38
2021 65
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2023 107
2024 97

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431 results

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Page 1
Malignant Glioma.
Wang LM, Englander ZK, Miller ML, Bruce JN. Wang LM, et al. Adv Exp Med Biol. 2023;1405:1-30. doi: 10.1007/978-3-031-23705-8_1. Adv Exp Med Biol. 2023. PMID: 37452933 Review.
In addition to well-established epidemiology, clinical manifestations, and common histopathologic and radiologic features of malignant gliomas, this section considers recent advances in molecular biology that have led to a more nuanced understanding of the genetic changes …
In addition to well-established epidemiology, clinical manifestations, and common histopathologic and radiologic features of malignant gliom …
Found in translation-Fibrosis in metabolic dysfunction-associated steatohepatitis (MASH).
Wang S, Friedman SL. Wang S, et al. Sci Transl Med. 2023 Oct 4;15(716):eadi0759. doi: 10.1126/scitranslmed.adi0759. Epub 2023 Oct 4. Sci Transl Med. 2023. PMID: 37792957 Free PMC article. Review.
Recent advances in single-cell methodologies, refined disease models, and genetic and epigenetic insights have provided a nuanced understanding of MASH fibrogenesis, with substantial cellular heterogeneity in MASH livers providing potentially targetable cell-cell interacti …
Recent advances in single-cell methodologies, refined disease models, and genetic and epigenetic insights have provided a nuanced und …
A proteogenomic portrait of lung squamous cell carcinoma.
Satpathy S, Krug K, Jean Beltran PM, Savage SR, Petralia F, Kumar-Sinha C, Dou Y, Reva B, Kane MH, Avanessian SC, Vasaikar SV, Krek A, Lei JT, Jaehnig EJ, Omelchenko T, Geffen Y, Bergstrom EJ, Stathias V, Christianson KE, Heiman DI, Cieslik MP, Cao S, Song X, Ji J, Liu W, Li K, Wen B, Li Y, Gümüş ZH, Selvan ME, Soundararajan R, Visal TH, Raso MG, Parra ER, Babur Ö, Vats P, Anand S, Schraink T, Cornwell M, Rodrigues FM, Zhu H, Mo CK, Zhang Y, da Veiga Leprevost F, Huang C, Chinnaiyan AM, Wyczalkowski MA, Omenn GS, Newton CJ, Schurer S, Ruggles KV, Fenyö D, Jewell SD, Thiagarajan M, Mesri M, Rodriguez H, Mani SA, Udeshi ND, Getz G, Suh J, Li QK, Hostetter G, Paik PK, Dhanasekaran SM, Govindan R, Ding L, Robles AI, Clauser KR, Nesvizhskii AI, Wang P, Carr SA, Zhang B, Mani DR, Gillette MA; Clinical Proteomic Tumor Analysis Consortium. Satpathy S, et al. Cell. 2021 Aug 5;184(16):4348-4371.e40. doi: 10.1016/j.cell.2021.07.016. Cell. 2021. PMID: 34358469 Free PMC article.
Proteogenomic dissection of CDKN2A mutations argue for more nuanced assessment of RB1 protein expression and phosphorylation before declaring CDK4/6 inhibition unsuccessful. ...
Proteogenomic dissection of CDKN2A mutations argue for more nuanced assessment of RB1 protein expression and phosphorylation before d …
Deep learning in clinical natural language processing: a methodical review.
Wu S, Roberts K, Datta S, Du J, Ji Z, Si Y, Soni S, Wang Q, Wei Q, Xiang Y, Zhao B, Xu H. Wu S, et al. J Am Med Inform Assoc. 2020 Mar 1;27(3):457-470. doi: 10.1093/jamia/ocz200. J Am Med Inform Assoc. 2020. PMID: 31794016 Free PMC article. Review.
A number of common associations were substantiated (eg, the preference of recurrent neural networks for sequence-labeling named entity recognition), while others were surprisingly nuanced (eg, the scarcity of French language clinical NLP with deep learning). ...
A number of common associations were substantiated (eg, the preference of recurrent neural networks for sequence-labeling named entity recog …
Virus diversity, wildlife-domestic animal circulation and potential zoonotic viruses of small mammals, pangolins and zoo animals.
Cui X, Fan K, Liang X, Gong W, Chen W, He B, Chen X, Wang H, Wang X, Zhang P, Lu X, Chen R, Lin K, Liu J, Zhai J, Liu DX, Shan F, Li Y, Chen RA, Meng H, Li X, Mi S, Jiang J, Zhou N, Chen Z, Zou JJ, Ge D, Yang Q, He K, Chen T, Wu YJ, Lu H, Irwin DM, Shen X, Hu Y, Lu X, Ding C, Guan Y, Tu C, Shen Y. Cui X, et al. Nat Commun. 2023 Apr 29;14(1):2488. doi: 10.1038/s41467-023-38202-4. Nat Commun. 2023. PMID: 37120646 Free PMC article.
Further, the potential cross-species transmission of RNA viruses (paramyxovirus and astrovirus) and DNA viruses (pseudorabies virus, porcine circovirus 2, porcine circovirus 3 and parvovirus) between wildlife and domestic animals was identified, complicating wildlife protection a …
Further, the potential cross-species transmission of RNA viruses (paramyxovirus and astrovirus) and DNA viruses (pseudorabies virus, porcine …
The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles.
Dilliard SA, Sun Y, Brown MO, Sung YC, Chatterjee S, Farbiak L, Vaidya A, Lian X, Wang X, Lemoff A, Siegwart DJ. Dilliard SA, et al. J Control Release. 2023 Sep;361:361-372. doi: 10.1016/j.jconrel.2023.07.058. Epub 2023 Aug 10. J Control Release. 2023. PMID: 37536547
Furthermore, changes to the chemical structure alter the quantities and identities of protein corona constituents in a manner that correlates with organ-targeting outcomes, with certain proteins appearing to promote lung targeting whereas others reduce delivery to off-target orga …
Furthermore, changes to the chemical structure alter the quantities and identities of protein corona constituents in a manner that correlate …
Sniping Cancer Stem Cells with Nanomaterials.
Wang WD, Guo YY, Yang ZL, Su GL, Sun ZJ. Wang WD, et al. ACS Nano. 2023 Dec 12;17(23):23262-23298. doi: 10.1021/acsnano.3c07828. Epub 2023 Nov 27. ACS Nano. 2023. PMID: 38010076 Review.
This review provides an update on the current landscape of nanobased precision targeting approaches against CSCs. We elucidate the nuanced application of organic, inorganic, and bioinspired nanomaterials across a spectrum of therapeutic paradigms, encompassing targeted the …
This review provides an update on the current landscape of nanobased precision targeting approaches against CSCs. We elucidate the nuance
Glucagon-like peptide-1 analogs: Miracle drugs are blooming?
Gong B, Yao Z, Zhou C, Wang W, Sun L, Han J. Gong B, et al. Eur J Med Chem. 2024 Apr 5;269:116342. doi: 10.1016/j.ejmech.2024.116342. Epub 2024 Mar 17. Eur J Med Chem. 2024. PMID: 38531211 Review.
This review summarizes the physiological functions of GLP-1, systematically explores diverse structural modifications, delves into the realm of unimolecular multi-agonists, and provides a nuanced portrayal of the developmental prospects that lie ahead for GLP-1 analogs....
This review summarizes the physiological functions of GLP-1, systematically explores diverse structural modifications, delves into the realm …
Surgical treatment of adrenal tumors during pregnancy.
Bartz-Kurycki MA, Dream S, Wang TS. Bartz-Kurycki MA, et al. Rev Endocr Metab Disord. 2023 Feb;24(1):107-120. doi: 10.1007/s11154-022-09744-7. Epub 2022 Jul 1. Rev Endocr Metab Disord. 2023. PMID: 35776233 Free PMC article. Review.
Achieving a diagnosis of hormone excess due to adrenal tumors can be clinically more difficult in the gravid patient due to normal physiologic alterations in hormones and symptoms related to pregnancy. This review focuses on some nuances of the diagnostic work-up, perioper …
Achieving a diagnosis of hormone excess due to adrenal tumors can be clinically more difficult in the gravid patient due to normal physiolog …
431 results