Surgical treatment of adrenal tumors during pregnancy

Rev Endocr Metab Disord. 2023 Feb;24(1):107-120. doi: 10.1007/s11154-022-09744-7. Epub 2022 Jul 1.

Abstract

While most adrenal tumors are identified incidentally and are non-functional, hormone-secreting tumors can cause morbidity and mortality. Hemodynamic lability and hypertension in pregnancy are associated with worse maternal and fetal outcomes. Achieving a diagnosis of hormone excess due to adrenal tumors can be clinically more difficult in the gravid patient due to normal physiologic alterations in hormones and symptoms related to pregnancy. This review focuses on some nuances of the diagnostic work-up, perioperative care, and surgical management of adrenally-mediated cortisol excess, primary aldosteronism, and pheochromocytoma and paraganglioma in the pregnant patient.

Keywords: Adrenal tumors; Adrenalectomy; Pheochromocytoma; Pregnancy.

Publication types

  • Review

MeSH terms

  • Adrenal Gland Neoplasms* / complications
  • Adrenal Gland Neoplasms* / diagnosis
  • Adrenal Gland Neoplasms* / surgery
  • Adrenalectomy
  • Female
  • Hormones
  • Humans
  • Hypertension*
  • Pheochromocytoma* / complications
  • Pheochromocytoma* / diagnosis
  • Pheochromocytoma* / surgery
  • Pregnancy

Substances

  • Hormones