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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 1
2008 1
2009 3
2012 2
2013 2
2014 2
2015 2
2016 5
2017 8
2018 4
2019 6
2020 8
2021 3
2022 5
2023 8
2024 4

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60 results

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Page 1
RNA Splicing and Cancer.
Wang E, Aifantis I. Wang E, et al. Trends Cancer. 2020 Aug;6(8):631-644. doi: 10.1016/j.trecan.2020.04.011. Epub 2020 May 17. Trends Cancer. 2020. PMID: 32434734 Review.
RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. ...
RNA splicing is an essential process that governs many aspects of cellular proliferation, survival, and differentiation. ...
AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review.
Targownik LE, Fisher DA, Saini SD. Targownik LE, et al. Gastroenterology. 2022 Apr;162(4):1334-1342. doi: 10.1053/j.gastro.2021.12.247. Epub 2022 Feb 17. Gastroenterology. 2022. PMID: 35183361 Review.
All co-authors reviewed, edited, and selected or rejected draft BPAs for inclusion in the final list submitted to the American Gastroenterological Association Governing Board. Because this was not a systematic review, we did not carry out a formal rating of the quality of …
All co-authors reviewed, edited, and selected or rejected draft BPAs for inclusion in the final list submitted to the American Gastroenterol …
Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway.
Kurppa KJ, Liu Y, To C, Zhang T, Fan M, Vajdi A, Knelson EH, Xie Y, Lim K, Cejas P, Portell A, Lizotte PH, Ficarro SB, Li S, Chen T, Haikala HM, Wang H, Bahcall M, Gao Y, Shalhout S, Boettcher S, Shin BH, Thai T, Wilkens MK, Tillgren ML, Mushajiang M, Xu M, Choi J, Bertram AA, Ebert BL, Beroukhim R, Bandopadhayay P, Awad MM, Gokhale PC, Kirschmeier PT, Marto JA, Camargo FD, Haq R, Paweletz CP, Wong KK, Barbie DA, Long HW, Gray NS, Jänne PA. Kurppa KJ, et al. Cancer Cell. 2020 Jan 13;37(1):104-122.e12. doi: 10.1016/j.ccell.2019.12.006. Cancer Cell. 2020. PMID: 31935369 Free PMC article.
Eradicating tumor dormancy that develops following epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) treatment of EGFR-mutant non-small cell lung cancer, is an attractive therapeutic strategy but the mechanisms governing this process are poorly unders …
Eradicating tumor dormancy that develops following epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) treatment of EGFR …
Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.
Pongor LS, Schultz CW, Rinaldi L, Wangsa D, Redon CE, Takahashi N, Fialkoff G, Desai P, Zhang Y, Burkett S, Hermoni N, Vilk N, Gutin J, Gergely R, Zhao Y, Nichols S, Vilimas R, Sciuto L, Graham C, Caravaca JM, Turan S, Tsai-Wei S, Rajapakse VN, Kumar R, Upadhyay D, Kumar S, Kim YS, Roper N, Tran B, Hewitt SM, Kleiner DE, Aladjem MI, Friedman N, Hager GL, Pommier Y, Ried T, Thomas A. Pongor LS, et al. Cancer Discov. 2023 Apr 3;13(4):928-949. doi: 10.1158/2159-8290.CD-22-0796. Cancer Discov. 2023. PMID: 36715552 Free PMC article.
Altogether, our work provides the first comprehensive map of SCLC ecDNA and describes a new mechanism that governs MYC-driven SCLC heterogeneity. ecDNA-enabled transcriptional flexibility may explain the significantly worse survival outcomes of SCLC harboring complex ecDNA …
Altogether, our work provides the first comprehensive map of SCLC ecDNA and describes a new mechanism that governs MYC-driven SCLC he …
Governing Global Antimicrobial Resistance: 6 Key Lessons From the Paris Climate Agreement.
Weldon I, Rogers Van Katwyk S, Burci GL, Giur D, de Campos TC, Eccleston-Turner M, Fryer HR, Giubilini A, Hale T, Harrison M, Johnson S, Kirchhelle C, Lee K, Liddell K, Mendelson M, Ooms G, Orbinski J, Piddock LJV, Røttingen JA, Savulescu J, Singer AC, Viens AM, Wenham C, Wiktorowicz ME, Zaidi S, Hoffman SJ. Weldon I, et al. Am J Public Health. 2022 Apr;112(4):553-557. doi: 10.2105/AJPH.2021.306695. Am J Public Health. 2022. PMID: 35319963 Free PMC article. No abstract available.
MicroRNA 155 and viral-induced neuroinflammation.
Dickey LL, Hanley TM, Huffaker TB, Ramstead AG, O'Connell RM, Lane TE. Dickey LL, et al. J Neuroimmunol. 2017 Jul 15;308:17-24. doi: 10.1016/j.jneuroim.2017.01.016. Epub 2017 Jan 24. J Neuroimmunol. 2017. PMID: 28139244 Free PMC article. Review.
MicroRNA (miRNA) regulation of gene expression is becoming an increasingly recognized mechanism by which host immune responses are governed following microbial infection. miRNAs are short, non-coding RNAs that repress translation of target genes, and have been implicated i …
MicroRNA (miRNA) regulation of gene expression is becoming an increasingly recognized mechanism by which host immune responses are govern …
3D Chromosomal Landscapes in Hematopoiesis and Immunity.
Kloetgen A, Thandapani P, Tsirigos A, Aifantis I. Kloetgen A, et al. Trends Immunol. 2019 Sep;40(9):809-824. doi: 10.1016/j.it.2019.07.003. Epub 2019 Aug 15. Trends Immunol. 2019. PMID: 31422902 Free PMC article. Review.
Here, we summarize the current principles of 3D chromatin organization, how the integrity of the 3D genome governs immune cell development and malignant transformation, as well as how underlying (epi-)genetic drivers of 3D chromatin alterations might act as potential novel …
Here, we summarize the current principles of 3D chromatin organization, how the integrity of the 3D genome governs immune cell develo …
Structural basis for self-discrimination by neoantigen-specific TCRs.
Finnigan JP, Newman JH, Patskovsky Y, Patskovska L, Ishizuka AS, Lynn GM, Seder RA, Krogsgaard M, Bhardwaj N. Finnigan JP, et al. Nat Commun. 2024 Mar 8;15(1):2140. doi: 10.1038/s41467-024-46367-9. Nat Commun. 2024. PMID: 38459027 Free PMC article.
T cell receptors (TCR) are pivotal in mediating tumour cell cytolysis via recognition of mutation-derived tumour neoantigens (neoAgs) presented by major histocompatibility class-I (MHC-I). Understanding the factors governing the emergence of neoAg from somatic mutations is …
T cell receptors (TCR) are pivotal in mediating tumour cell cytolysis via recognition of mutation-derived tumour neoantigens (neoAgs) presen …
Tissue engineering the cancer microenvironment-challenges and opportunities.
Papalazarou V, Salmeron-Sanchez M, Machesky LM. Papalazarou V, et al. Biophys Rev. 2018 Dec;10(6):1695-1711. doi: 10.1007/s12551-018-0466-8. Epub 2018 Nov 8. Biophys Rev. 2018. PMID: 30406572 Free PMC article. Review.
We argue that by gaining a better understanding of the microenvironment and the mechanical forces that govern tumour dynamics, we can make advances in combatting cancer dormancy, recurrence and metastasis....
We argue that by gaining a better understanding of the microenvironment and the mechanical forces that govern tumour dynamics, we can …
Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation.
Mehta B, Goodman S, DiCarlo E, Jannat-Khah D, Gibbons JAB, Otero M, Donlin L, Pannellini T, Robinson WH, Sculco P, Figgie M, Rodriguez J, Kirschmann JM, Thompson J, Slater D, Frezza D, Xu Z, Wang F, Orange DE. Mehta B, et al. Arthritis Res Ther. 2023 Mar 2;25(1):31. doi: 10.1186/s13075-023-03008-8. Arthritis Res Ther. 2023. PMID: 36864474 Free PMC article.
60 results