In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System.
Knöspel F, Jacobs F, Freyer N, Damm G, De Bondt A, van den Wyngaert I, Snoeys J, Monshouwer M, Richter M, Strahl N, Seehofer D, Zeilinger K.
Knöspel F, et al.
Int J Mol Sci. 2016 Apr 16;17(4):584. doi: 10.3390/ijms17040584.
Int J Mol Sci. 2016.
PMID: 27092500
Free PMC article.
Formation rates of diclofenac metabolites were relatively stable over the application period of seven days in bioreactors exposed to 300 M diclofenac (300 M bioreactors (300 M BR)), while in bioreactors exposed to 1000 M diclofenac (1000 M BR) metabolite concentrations declined …
Formation rates of diclofenac metabolites were relatively stable over the application period of seven days in bioreactors exposed to 300 M d …