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Contact Dermatitis to Medications and Skin Products.
Nguyen HL, Yiannias JA. Nguyen HL, et al. Clin Rev Allergy Immunol. 2019 Feb;56(1):41-59. doi: 10.1007/s12016-018-8705-0. Clin Rev Allergy Immunol. 2019. PMID: 30145645 Review.
Finally, we examine the ingredients in the excipients of these products, such as the formaldehyde releasers (quaternium-15, 2-bromo-2-nitropropane-1,3 diol, diazolidinyl urea, imidazolidinyl urea, DMDM hydantoin), the non-formaldehyde releasers (isothiazolinones, parabens, …
Finally, we examine the ingredients in the excipients of these products, such as the formaldehyde releasers (quaternium-15, 2-bromo-2-nitrop …
Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.
Schumacher M, Weill-Engerer S, Liere P, Robert F, Franklin RJ, Garcia-Segura LM, Lambert JJ, Mayo W, Melcangi RC, Parducz A, Suter U, Carelli C, Baulieu EE, Akwa Y. Schumacher M, et al. Prog Neurobiol. 2003 Sep;71(1):3-29. doi: 10.1016/j.pneurobio.2003.09.004. Prog Neurobiol. 2003. PMID: 14611864 Review.
The conversion of dehydroepiandrosterone to Delta5-androstene-3beta,17beta-diol and to 7alpha-OH-dehydroepiandrosterone occurred in frontal cortex, hippocampus, amygdala, cerebellum and striatum of both Alzheimer's patients and controls. ...
The conversion of dehydroepiandrosterone to Delta5-androstene-3beta,17beta-diol and to 7alpha-OH-dehydroepiandrosterone occurred in f …
Metabolite releasing polymers control dendritic cell function by modulating their energy metabolism.
Mangal JL, Inamdar S, Yang Y, Dutta S, Wankhede M, Shi X, Gu H, Green M, Rege K, Curtis M, Acharya AP. Mangal JL, et al. J Mater Chem B. 2020 Jun 24;8(24):5195-5203. doi: 10.1039/d0tb00790k. J Mater Chem B. 2020. PMID: 32427266 Free PMC article.
Metabolites control immune cell functions, and delivery of these metabolites in a sustained manner may be able to modulate function of the immune cells. In this study, alpha-ketoglutarate (aKG) and diol based polymeric-microparticles (termed paKG MPs) were synthesized to p …
Metabolites control immune cell functions, and delivery of these metabolites in a sustained manner may be able to modulate function of the i …
Trends in patch-test results and allergen changes in the standard series: a Mayo Clinic 5-year retrospective review (January 1, 2006, to December 31, 2010).
Wentworth AB, Yiannias JA, Keeling JH, Hall MR, Camilleri MJ, Drage LA, Torgerson RR, Fett DD, Prakash AV, Scalf LA, Allen EM, Johnson JS, Singh N, Nordberg Linehan DL, Killian JM, Davis MD. Wentworth AB, et al. J Am Acad Dermatol. 2014 Feb;70(2):269-75.e4. doi: 10.1016/j.jaad.2013.09.047. Epub 2013 Nov 20. J Am Acad Dermatol. 2014. PMID: 24268786
Rates were lower for 10 allergens: neomycin sulfate, 20%; gold sodium thiosulfate, 0.5%; hexahydro-1,3,5-tris(2-hydroxyethyl)triazine, 1%; disperse blue 124, 1%; disperse blue 106, 1%; diazolidinyl urea, 1%; hexylresorcinol, 0.25%; diazolidinyl urea, 1% aqueous; 2-bromo-2-nitropr …
Rates were lower for 10 allergens: neomycin sulfate, 20%; gold sodium thiosulfate, 0.5%; hexahydro-1,3,5-tris(2-hydroxyethyl)triazine, 1%; d …
Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
Upadhyaya P, Kenney PM, Hochalter JB, Wang M, Hecht SS. Upadhyaya P, et al. Carcinogenesis. 1999 Aug;20(8):1577-82. doi: 10.1093/carcin/20.8.1577. Carcinogenesis. 1999. PMID: 10426810
In this study, we assessed the relative tumorigenic activities in the A/J mouse of NNK, racemic NNAL, (R)-NNAL, (S)-NNAL and several NNAL metabolites, including [4-(methylnitrosamino)-1-(3-pyridyl)but-(S)-1-yl] beta-O-D-gluco-siduronic acid [(S)-NNAL-Gluc], 4-(methylnitrosamino)- …
In this study, we assessed the relative tumorigenic activities in the A/J mouse of NNK, racemic NNAL, (R)-NNAL, (S)-NNAL and several NNAL me …
Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study.
Bressler J, Yu B, Mosley TH, Knopman DS, Gottesman RF, Alonso A, Sharrett AR, Wruck LM, Boerwinkle E. Bressler J, et al. Transl Psychiatry. 2017 Jul 18;7(7):e1173. doi: 10.1038/tp.2017.118. Transl Psychiatry. 2017. PMID: 28934192 Free PMC article.
Two unnamed compounds and three sex steroid hormones were associated with an increased risk of dementia (all P<3.9 10(-4)). The association of 4-androstene-3beta, 17beta-diol disulfate 1 with dementia was replicated in European Americans. ...
Two unnamed compounds and three sex steroid hormones were associated with an increased risk of dementia (all P<3.9 10(-4)). The associati …
Effects of benzyl isothiocyanate and phenethyl isothiocyanate on benzo[a]pyrene metabolism and DNA adduct formation in the A/J mouse.
Sticha KR, Staretz ME, Wang M, Liang H, Kenney PM, Hecht SS. Sticha KR, et al. Carcinogenesis. 2000 Sep;21(9):1711-9. doi: 10.1093/carcin/21.9.1711. Carcinogenesis. 2000. PMID: 10964103
In lung, 6 h after treatment, B[a]P-7, 8-diol and some other metabolites were inhibited by BITC and PEITC. However, 24 h after treatment, no inhibition of B[a]P-7,8-diol was observed in microsomes from BITC-treated mice, whereas it was substantially increased in mic …
In lung, 6 h after treatment, B[a]P-7, 8-diol and some other metabolites were inhibited by BITC and PEITC. However, 24 h after treatm …
Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms.
Hecht SS, Villalta PW, Hochalter JB. Hecht SS, et al. Carcinogenesis. 2008 May;29(5):937-43. doi: 10.1093/carcin/bgn015. Epub 2008 May 13. Carcinogenesis. 2008. PMID: 18477646 Free PMC article.
We prepared standard mercapturic acids by reactions of syn- or anti-Phe-1,2-diol-3,4-epoxide and syn- or anti-Phe-3,4-diol-1,2-epoxide with N-acetylcysteine. Analysis of human urine conclusively demonstrated that the only detectable mercapturic acid of this type--N- …
We prepared standard mercapturic acids by reactions of syn- or anti-Phe-1,2-diol-3,4-epoxide and syn- or anti-Phe-3,4-diol-1,2 …
Estrogen increases nitric-oxide production in human bronchial epithelium.
Townsend EA, Meuchel LW, Thompson MA, Pabelick CM, Prakash YS. Townsend EA, et al. J Pharmacol Exp Ther. 2011 Dec;339(3):815-24. doi: 10.1124/jpet.111.184416. Epub 2011 Sep 22. J Pharmacol Exp Ther. 2011. PMID: 21940647 Free PMC article.
Estrogen receptor (ER) isoform-specific agonists (R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol (THC) (ERalpha) and diaryl-propionitrile (DPN) (ERbeta) stimulated NO production to comparable levels and at comparable rates, whereas the ER antagonist 7alpha,17beta-[9-[(4, …
Estrogen receptor (ER) isoform-specific agonists (R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol (THC) (ERalpha) and diaryl-propion …
Preclinical pharmacologic studies of the new antitumor agent carmethizole (NSC-602668) in the mouse and beagle dog.
Brodfuehrer JI, Wilke TJ, Kinder DH, Powis G. Brodfuehrer JI, et al. Cancer Chemother Pharmacol. 1989;24(5):277-83. doi: 10.1007/BF00304758. Cancer Chemother Pharmacol. 1989. PMID: 2758557
Its major breakdown product in 0.9% sodium chloride and pH 5.0 sodium phosphate buffer was carmethizole diol. When carmethizole was added to pH 7.0 or pH 9.0 sodium phosphate buffer, the major breakdown product was carmethizole diol-4'-monophosphate. ...Following th …
Its major breakdown product in 0.9% sodium chloride and pH 5.0 sodium phosphate buffer was carmethizole diol. When carmethizole was a …
15 results