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Page 1
Synthesis of vaniprevir (MK-7009): lactamization to prepare a 20-membered [corrected] macrocycle.
J Org Chem. 2011 Oct 7;76(19):7804-15. doi: 10.1021/jo2011494. Epub 2011 Aug 31.
J Org Chem. 2011.
PMID: 21838271
Efficient and practical synthesis of (R)-2-methylpyrrolidine.
Zhao D, Kuethe JT, Journet M, Peng Z, Humphrey GR.
Zhao D, et al.
J Org Chem. 2006 May 26;71(11):4336-8. doi: 10.1021/jo060319n.
J Org Chem. 2006.
PMID: 16709084
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Stereoselective formation of carbon-carbon bonds via SN2-displacement: synthesis of substituted cycloalkyl[b]indoles.
Hillier MC, Marcoux JF, Zhao D, Grabowski EJ, McKeown AE, Tillyer RD.
Hillier MC, et al. Among authors: zhao d.
J Org Chem. 2005 Oct 14;70(21):8385-94. doi: 10.1021/jo051146p.
J Org Chem. 2005.
PMID: 16209582
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Practical asymmetric synthesis of a potent PDE4 inhibitor via stereoselective enolate alkylation of a chiral aryl-heteroaryl secondary tosylate.
O'Shea PD, Chen CY, Chen W, Dagneau P, Frey LF, Grabowski EJ, Marcantonio KM, Reamer RA, Tan L, Tillyer RD, Roy A, Wang X, Zhao D.
O'Shea PD, et al. Among authors: zhao d.
J Org Chem. 2005 Apr 15;70(8):3021-30. doi: 10.1021/jo048156v.
J Org Chem. 2005.
PMID: 15822960
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Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease.
Mark BL, Mahuran DJ, Cherney MM, Zhao D, Knapp S, James MN.
Mark BL, et al. Among authors: zhao d.
J Mol Biol. 2003 Apr 11;327(5):1093-109. doi: 10.1016/s0022-2836(03)00216-x.
J Mol Biol. 2003.
PMID: 12662933
Free PMC article.
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Asymmetric Diels-Alder reactions of chiral cyclopropylidene imide dienophiles: preparation of gem-dimethyl- and spirocyclopropane norbornyl carboxylic acids.
Kuethe JT, Zhao D, Humphrey GR, Journet M, McKeown AE.
Kuethe JT, et al. Among authors: zhao d.
J Org Chem. 2006 Mar 3;71(5):2192-5. doi: 10.1021/jo052516c.
J Org Chem. 2006.
PMID: 16497018
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