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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1983 1
1988 2
1991 1
1993 2
1994 2
1995 4
1996 6
1997 4
1998 14
1999 17
2000 18
2001 32
2002 41
2003 61
2004 83
2005 108
2006 125
2007 121
2008 119
2009 137
2010 162
2011 179
2012 197
2013 278
2014 396
2015 446
2016 485
2017 469
2018 527
2019 590
2020 643
2021 707
2022 731
2023 637
2024 287

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6,784 results

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Page 1
DEAH-Box RNA Helicases in Pre-mRNA Splicing.
De Bortoli F, Espinosa S, Zhao R. De Bortoli F, et al. Trends Biochem Sci. 2021 Mar;46(3):225-238. doi: 10.1016/j.tibs.2020.10.006. Epub 2020 Nov 30. Trends Biochem Sci. 2021. PMID: 33272784 Free PMC article. Review.
These crucial rearrangements are largely driven by eight DExD/H-box RNA helicases. Interestingly, the four helicases participating in the late stages of splicing are all DEAH-box helicases that share structural similarities. This review aims to provide an overview o …
These crucial rearrangements are largely driven by eight DExD/H-box RNA helicases. Interestingly, the four helicases participating in …
DDX39B drives colorectal cancer progression by promoting the stability and nuclear translocation of PKM2.
Zhao G, Yuan H, Li Q, Zhang J, Guo Y, Feng T, Gu R, Ou D, Li S, Li K, Lin P. Zhao G, et al. Signal Transduct Target Ther. 2022 Aug 17;7(1):275. doi: 10.1038/s41392-022-01096-7. Signal Transduct Target Ther. 2022. PMID: 35973989 Free PMC article.
We demonstrate that Sp1 potently activates DDX39B transcription by directly binding to the GC box of the DDX39B promoter in CRC cells. DDX39B overexpression augments the proliferation, migration, and invasion of CRC cells, while the opposite results are obtained in DDX39B- …
We demonstrate that Sp1 potently activates DDX39B transcription by directly binding to the GC box of the DDX39B promoter in CRC cells …
LncRNA HIF1A-AS1 Promotes Gemcitabine Resistance of Pancreatic Cancer by Enhancing Glycolysis through Modulating the AKT/YB1/HIF1α Pathway.
Xu F, Huang M, Chen Q, Niu Y, Hu Y, Hu P, Chen D, He C, Huang K, Zeng Z, Tang J, Wang F, Zhao Y, Wang C, Zhao G. Xu F, et al. Cancer Res. 2021 Nov 15;81(22):5678-5691. doi: 10.1158/0008-5472.CAN-21-0281. Epub 2021 Sep 30. Cancer Res. 2021. PMID: 34593522
Mechanistically, HIF1A-AS1 facilitated the interaction between serine/threonine kinase AKT and Y-box-binding protein 1 (YB1), which promoted phosphorylation of YB1 (pYB1). ...
Mechanistically, HIF1A-AS1 facilitated the interaction between serine/threonine kinase AKT and Y-box-binding protein 1 (YB1), which p …
HMGB1 in kidney diseases.
Zhao Z, Hu Z, Zeng R, Yao Y. Zhao Z, et al. Life Sci. 2020 Oct 15;259:118203. doi: 10.1016/j.lfs.2020.118203. Epub 2020 Aug 8. Life Sci. 2020. PMID: 32781069 Review.
High mobility group box 1 (HMGB1) is a highly conserved nucleoprotein involving in numerous biological processes, and well known to trigger immune responses as the damage-associated molecular pattern (DAMP) in the extracellular environment. ...
High mobility group box 1 (HMGB1) is a highly conserved nucleoprotein involving in numerous biological processes, and well known to t …
The roles of NOP56 in cancer and SCA36.
Zhao S, Zhang D, Liu S, Huang J. Zhao S, et al. Pathol Oncol Res. 2023 Jan 19;29:1610884. doi: 10.3389/pore.2023.1610884. eCollection 2023. Pathol Oncol Res. 2023. PMID: 36741964 Free PMC article. Review.
ISGylation of NF-κBp65 by SCFFBXL19 E3 Ligase Diminishes Endothelial Inflammation.
Li L, Miao J, Shaheen N, Taleb SJ, Hu J, Ye Q, He J, Yan J, Mallampalli RK, Zhao J, Zhao Y. Li L, et al. Arterioscler Thromb Vasc Biol. 2023 May;43(5):674-683. doi: 10.1161/ATVBAHA.122.318894. Epub 2023 Mar 30. Arterioscler Thromb Vasc Biol. 2023. PMID: 36994728 Free PMC article.
TNFalpha (tumor necrosis factor alpha) and endotoxin stimulation of EC reduce p65 ISGylation, promoting its serine phosphorylation through reducing its association with a phosphatase WIP1 (wild-type p53-induced phosphatase 1). Mechanistically, an SCF (Skp1-Cul1-F-box) prot …
TNFalpha (tumor necrosis factor alpha) and endotoxin stimulation of EC reduce p65 ISGylation, promoting its serine phosphorylation through r …
Genome-wide identification and analysis of MIKC-type MADS-box genes expression in Chimonanthus salicifolius.
Gui FF, Jiang GG, Bin Dong, Zhong SW, Xiao Z, Qiu Fang, Wang YG, Yang LY, Zhao H. Gui FF, et al. Genes Genomics. 2023 Sep;45(9):1127-1141. doi: 10.1007/s13258-023-01420-7. Epub 2023 Jul 12. Genes Genomics. 2023. PMID: 37438657
BACKGROUND: MIKC type MADS-box transcription factors are one of the largest gene families and play a pivotal role in flowering time and flower development. ...MIKC-type MADS-box genes from the same subfamily share similar distribution patterns, gene structure, and e …
BACKGROUND: MIKC type MADS-box transcription factors are one of the largest gene families and play a pivotal role in flowering time a …
SRY protein function in sex determination: thinking outside the box.
Zhao L, Koopman P. Zhao L, et al. Chromosome Res. 2012 Jan;20(1):153-62. doi: 10.1007/s10577-011-9256-x. Chromosome Res. 2012. PMID: 22161124 Review.
Even though the mammalian sex-determining gene Sry has been intensively studied for the two decades since its discovery, the regions outside the conserved HMG box DNA-binding domain have received less attention due to a lack of sequence conservation and of obvious structur …
Even though the mammalian sex-determining gene Sry has been intensively studied for the two decades since its discovery, the regions outside …
The characteristics and roles of β-TrCP1/2 in carcinogenesis.
Bi Y, Cui D, Xiong X, Zhao Y. Bi Y, et al. FEBS J. 2021 Jun;288(11):3351-3374. doi: 10.1111/febs.15585. Epub 2020 Oct 23. FEBS J. 2021. PMID: 33021036 Free article. Review.
beta-transducin repeat-containing protein (beta-TrCP), one of the well-characterized F-box proteins, acts as a substrate receptor and constitutes an active SCF(beta-TrCP) E3 ligase with a scaffold protein CUL1, a RING protein RBX1, and an adaptor protein SKP1. beta-TrCP pl …
beta-transducin repeat-containing protein (beta-TrCP), one of the well-characterized F-box proteins, acts as a substrate receptor and …
Precise characterization of GlnR Box in actinomycetes.
Wang J, Wang Y, Zhao GP. Wang J, et al. Biochem Biophys Res Commun. 2015 Mar 13;458(3):605-607. doi: 10.1016/j.bbrc.2015.02.010. Epub 2015 Feb 13. Biochem Biophys Res Commun. 2015. PMID: 25684190
Site-by-site mutagenesis strategy combining with the Electrophoretic Mobility Shift Assay were employed, and a 5-nt GlnR Box was precisely defined as the basic unit for GlnR binding....
Site-by-site mutagenesis strategy combining with the Electrophoretic Mobility Shift Assay were employed, and a 5-nt GlnR Box was prec …
6,784 results