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Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo.
Ni H, Hatit MZC, Zhao K, Loughrey D, Lokugamage MP, Peck HE, Cid AD, Muralidharan A, Kim Y, Santangelo PJ, Dahlman JE. Ni H, et al. Among authors: muralidharan a. Nat Commun. 2022 Aug 15;13(1):4766. doi: 10.1038/s41467-022-32281-5. Nat Commun. 2022. PMID: 35970837 Free PMC article.
Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heart.
Radmand A, Kim H, Beyersdorf J, Dobrowolski CN, Zenhausern R, Paunovska K, Huayamares SG, Hua X, Han K, Loughrey D, Hatit MZC, Del Cid A, Ni H, Shajii A, Li A, Muralidharan A, Peck HE, Tiegreen KE, Jia S, Santangelo PJ, Dahlman JE. Radmand A, et al. Among authors: muralidharan a. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307801120. doi: 10.1073/pnas.2307801120. Epub 2024 Mar 4. Proc Natl Acad Sci U S A. 2024. PMID: 38437539 Free PMC article.