Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 1
2008 2
2009 3
2010 2
2013 2
2014 2
2015 1
2018 1
2019 3
2020 1
2021 3
2022 6
2023 4
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

28 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for valid hashimi
Search for Valid Hasyimi instead (1 results)
Measuring thermodynamic preferences to form non-native conformations in nucleic acids using ultraviolet melting.
Rangadurai A, Shi H, Xu Y, Liu B, Abou Assi H, Boom JD, Zhou H, Kimsey IJ, Al-Hashimi HM. Rangadurai A, et al. Proc Natl Acad Sci U S A. 2022 Jun 14;119(24):e2112496119. doi: 10.1073/pnas.2112496119. Epub 2022 Jun 7. Proc Natl Acad Sci U S A. 2022. PMID: 35671421 Free PMC article.
The key to this "delta-melt" approach is to use chemical modifications to render specific minor non-native conformations the major state. The validity and robustness of delta-melt is established for four different non-native conformations under various physiological condit …
The key to this "delta-melt" approach is to use chemical modifications to render specific minor non-native conformations the major state. Th …
DAT and TH expression marks human Parkinson's disease in peripheral immune cells.
Gopinath A, Mackie P, Hashimi B, Buchanan AM, Smith AR, Bouchard R, Shaw G, Badov M, Saadatpour L, Gittis A, Ramirez-Zamora A, Okun MS, Streit WJ, Hashemi P, Khoshbouei H. Gopinath A, et al. NPJ Parkinsons Dis. 2022 Jun 7;8(1):72. doi: 10.1038/s41531-022-00333-8. NPJ Parkinsons Dis. 2022. PMID: 35672374 Free PMC article.
Parkinson's disease (PD) is marked by a loss of dopamine neurons, decreased dopamine transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation approach cannot be used for diagnostic, drug effectiveness or investigational purposes in human patient …
Parkinson's disease (PD) is marked by a loss of dopamine neurons, decreased dopamine transporter (DAT) and tyrosine hydroxylase (TH) express …
Screening for diabetes and impaired glucose metabolism in Qatar: Models' development and validation.
Sadek K, Abdelhafez I, Al-Hashimi I, Al-Shafi W, Tarmizi F, Al-Marri H, Alzohari N, Balideh M, Carr A. Sadek K, et al. Prim Care Diabetes. 2022 Feb;16(1):69-77. doi: 10.1016/j.pcd.2021.10.002. Epub 2021 Oct 27. Prim Care Diabetes. 2022. PMID: 34716113
Another sample of 1000 participants was obtained for external validation of the models. Several scoring models screening for T2DM were evaluated and compared to the model proposed by this study. ...The QDMRISK performed well with area under the curve (AUC) 0.870 and .815 i …
Another sample of 1000 participants was obtained for external validation of the models. Several scoring models screening for T2DM wer …
NMR Chemical Exchange Measurements Reveal That N6-Methyladenosine Slows RNA Annealing.
Shi H, Liu B, Nussbaumer F, Rangadurai A, Kreutz C, Al-Hashimi HM. Shi H, et al. J Am Chem Soc. 2019 Dec 26;141(51):19988-19993. doi: 10.1021/jacs.9b10939. Epub 2019 Dec 16. J Am Chem Soc. 2019. PMID: 31826614 Free PMC article.
Here, we used NMR R(1rho) relaxation dispersion and chemical exchange saturation transfer to noninvasively and site-specifically measure nucleic acid hybridization kinetics. The methodology was validated on two DNA duplexes and then applied to examine how a single m(6)A al …
Here, we used NMR R(1rho) relaxation dispersion and chemical exchange saturation transfer to noninvasively and site-specifically measure nuc …
QSAR-guided pharmacophoric modeling reveals important structural requirements for Polo kinase 1 (Plk1) inhibitors.
Shahin R, Al-Hashimi NN, Daoud NE, Aljamal S, Shaheen O. Shahin R, et al. J Mol Graph Model. 2021 Dec;109:108022. doi: 10.1016/j.jmgm.2021.108022. Epub 2021 Sep 18. J Mol Graph Model. 2021. PMID: 34562852
The most successful QSAR model was with statistical criteria of (r(2)(277) = 0.76, r(2)adj = 0.76, r(2)pred = 0.75, Q(2) = 0.73). Our QSAR-selected pharmacophores were validated by Receiver Operating Characteristic (ROC) curve analysis. ...
The most successful QSAR model was with statistical criteria of (r(2)(277) = 0.76, r(2)adj = 0.76, r(2)pred = 0.75, Q(2) = 0.73). Our QSAR-s …
Truncated conjugation in fused heterocycle-based conducting polymers: when greater planarity does not enhance conjugation.
Marin-Beloqui JM, Gómez S, Gonev HI, Comí M, Al-Hashimi M, Clarke TM. Marin-Beloqui JM, et al. Chem Sci. 2022 Dec 7;14(4):812-821. doi: 10.1039/d2sc06271b. eCollection 2023 Jan 25. Chem Sci. 2022. PMID: 36755723 Free PMC article.
Conventionally, a more planar monomer structure induces a larger backbone coplanarity, thus leading to a greater overlap of the carbon pi-orbitals and therefore a higher degree of pi-electron delocalisation. However, here we present a case that counters the validity of thi …
Conventionally, a more planar monomer structure induces a larger backbone coplanarity, thus leading to a greater overlap of the carbon pi-or …
Integrating Network Pharmacology and Molecular Docking Approaches to Decipher the Multi-Target Pharmacological Mechanism of Abrus precatorius L. Acting on Diabetes.
Noor F, Rehman A, Ashfaq UA, Saleem MH, Okla MK, Al-Hashimi A, AbdElgawad H, Aslam S. Noor F, et al. Pharmaceuticals (Basel). 2022 Mar 29;15(4):414. doi: 10.3390/ph15040414. Pharmaceuticals (Basel). 2022. PMID: 35455411 Free PMC article.
In the framework of this study, we explored the active ingredient-target-pathway network and figured out that abrectorin, abrusin, abrisapogenol J, sophoradiol, cholanoic acid, precatorine, and cycloartenol decisively contributed to the development of T2DM by affecting AKT1, MAPK …
In the framework of this study, we explored the active ingredient-target-pathway network and figured out that abrectorin, abrusin, abrisapog …
Simultaneous determination of furosemide and carbamazepine in biological matrices by solvent bar microextraction combined with high-performance liquid chromatography-diode array detector and central composite design.
Al-Hashimi NN, Al-Degs YS, Jaafreh S, Al-Khatib HS, El-Sheikh AH, Abdelghani JI, Jaber MR. Al-Hashimi NN, et al. Biomed Chromatogr. 2022 Nov;36(11):e5476. doi: 10.1002/bmc.5476. Epub 2022 Aug 22. Biomed Chromatogr. 2022. PMID: 35918842
A comparison against published methods was also performed and the results revealed that the developed method exhibits a confident sensitivity, feasible operation, and simple analysis for both drugs. Finally, the practicability of the validated SBME-HPLC-DAD method was demo …
A comparison against published methods was also performed and the results revealed that the developed method exhibits a confident sensitivit …
Synthesis and Characterization of Methoxy-Exfoliated Montmorillonite Nanosheets as Potential Carriers of 5-Fluorouracil Drug with Enhanced Loading, Release, and Cytotoxicity Properties.
Alqahtani MD, Bin Jumah MN, Al-Hashimi A, Allam AA, Abukhadra MR, Bellucci S. Alqahtani MD, et al. Molecules. 2023 Aug 5;28(15):5895. doi: 10.3390/molecules28155895. Molecules. 2023. PMID: 37570864 Free PMC article.
Based on the release kinetic modeling, the release reactions exhibit non-Fickian transport release properties, validating cooperative diffusion and erosion release mechanisms. The cytotoxicity of 5-Fu is also significantly enhanced by these carriers: 5-Fu/BE (8.6% cell via …
Based on the release kinetic modeling, the release reactions exhibit non-Fickian transport release properties, validating cooperative …
Inner filter effect as a sensitive sensing platform for detection of nitrofurantoin using luminescent drug-based carbon nanodots.
Al-Hashimi BR, Omer KM, Rahman HS, Othman HH. Al-Hashimi BR, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2021 Jan 5;244:118835. doi: 10.1016/j.saa.2020.118835. Epub 2020 Aug 17. Spectrochim Acta A Mol Biomol Spectrosc. 2021. PMID: 32860993
The linear response for the proposed method was from 5.0 muM to 90 muM with the detection limit being 1.4 muM. To validate the method, the recovery of NIT in spiked sample was measured which was 96.6% -103.3%. ...
The linear response for the proposed method was from 5.0 muM to 90 muM with the detection limit being 1.4 muM. To validate the method …
28 results