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Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study).
Cieuta-Walti C, Cuenca-Royo A, Langohr K, Rakic C, López-Vílchez MÁ, Lirio J, González-Lamuño Leguina D, González TB, García JG, Roure MR, Aldea-Perona A, Forcano L, Gomis-Gonzalez M, Cés SV, Lacaille F, Ravel A, Mircher C, Walti H, Janel N, Dairou J, Lévy M, Durand S, Dierssen M, Sacco S, Fornell RT; PERSEUS Study Group. Cieuta-Walti C, et al. Among authors: ces sv. Genet Med. 2022 Oct;24(10):2004-2013. doi: 10.1016/j.gim.2022.06.011. Epub 2022 Aug 11. Genet Med. 2022. PMID: 35951014 Free article. Clinical Trial.
Longitudinal Clinical and Cognitive Changes Along the Alzheimer Disease Continuum in Down Syndrome.
Videla L, Benejam B, Pegueroles J, Carmona-Iragui M, Padilla C, Fernández S, Barroeta I, Altuna M, Valldeneu S, Garzón D, Ribas L, Montal V, Arranz Martínez J, Rozalem Aranha M, Alcolea D, Bejanin A, Iulita MF, Videla Cés S, Blesa R, Lleó A, Fortea J. Videla L, et al. Among authors: videla ces s. JAMA Netw Open. 2022 Aug 1;5(8):e2225573. doi: 10.1001/jamanetworkopen.2022.25573. JAMA Netw Open. 2022. PMID: 35930282 Free PMC article.