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Page 1
Many Activities, One Structure: Functional Plasticity of Ribozyme Folds.
Molecules. 2016 Nov 18;21(11):1570. doi: 10.3390/molecules21111570.
Molecules. 2016.
PMID: 27869745
Free PMC article.
Review.
In vitro evolution of coenzyme-independent variants from the glmS ribozyme structural scaffold.
Lau MW, Ferré-D'Amaré AR.
Lau MW, et al.
Methods. 2016 Aug 15;106:76-81. doi: 10.1016/j.ymeth.2016.04.027. Epub 2016 Apr 26.
Methods. 2016.
PMID: 27130889
Free PMC article.
Item in Clipboard
Structural basis for high-affinity fluorophore binding and activation by RNA Mango.
Trachman RJ 3rd, Demeshkina NA, Lau MWL, Panchapakesan SSS, Jeng SCY, Unrau PJ, Ferré-D'Amaré AR.
Trachman RJ 3rd, et al. Among authors: lau mwl.
Nat Chem Biol. 2017 Jul;13(7):807-813. doi: 10.1038/nchembio.2392. Epub 2017 May 29.
Nat Chem Biol. 2017.
PMID: 28553947
Free PMC article.
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An in vitro evolved glmS ribozyme has the wild-type fold but loses coenzyme dependence.
Lau MW, Ferré-D'Amaré AR.
Lau MW, et al.
Nat Chem Biol. 2013 Dec;9(12):805-10. doi: 10.1038/nchembio.1360. Epub 2013 Oct 6.
Nat Chem Biol. 2013.
PMID: 24096303
Free PMC article.
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A promiscuous ribozyme promotes nucleotide synthesis in addition to ribose chemistry.
Lau MW, Unrau PJ.
Lau MW, et al.
Chem Biol. 2009 Aug 28;16(8):815-25. doi: 10.1016/j.chembiol.2009.07.005.
Chem Biol. 2009.
PMID: 19716472
Item in Clipboard
A divalent cation-dependent variant of the glmS ribozyme with stringent Ca2+ selectivity co-opts a preexisting nonspecific metal ion-binding site.
Lau MW, Trachman RJ 3rd, Ferré-D'Amaré AR.
Lau MW, et al.
RNA. 2017 Mar;23(3):355-364. doi: 10.1261/rna.059824.116. Epub 2016 Dec 8.
RNA. 2017.
PMID: 27932587
Free PMC article.
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Isolation of fast purine nucleotide synthase ribozymes.
Lau MW, Cadieux KE, Unrau PJ.
Lau MW, et al.
J Am Chem Soc. 2004 Dec 8;126(48):15686-93. doi: 10.1021/ja045387a.
J Am Chem Soc. 2004.
PMID: 15571390
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