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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 7
2003 4
2004 2
2005 2
2006 3
2007 6
2008 5
2009 4
2010 5
2011 10
2012 9
2013 12
2014 10
2015 14
2016 11
2017 13
2018 14
2019 7
2020 14
2021 21
2022 14
2023 4
2024 2

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181 results

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Page 1
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.
Sharma S, Chung CY, Uryu S, Petrovic J, Cao J, Rickard A, Nady N, Greasley S, Johnson E, Brodsky O, Khan S, Wang H, Wang Z, Zhang Y, Tsaparikos K, Chen L, Mazurek A, Lapek J, Kung PP, Sutton S, Richardson PF, Greenwald EC, Yamazaki S, Jones R, Maegley KA, Bingham P, Lam H, Stupple AE, Kamal A, Chueh A, Cuzzupe A, Morrow BJ, Ren B, Carrasco-Pozo C, Tan CW, Bhuva DD, Allan E, Surgenor E, Vaillant F, Pehlivanoglu H, Falk H, Whittle JR, Newman J, Cursons J, Doherty JP, White KL, MacPherson L, Devlin M, Dennis ML, Hattarki MK, De Silva M, Camerino MA, Butler MS, Dolezal O, Pilling P, Foitzik R, Stupple PA, Lagiakos HR, Walker SR, Hediyeh-Zadeh S, Nuttall S, Spall SK, Charman SA, Connor T, Peat TS, Avery VM, Bozikis YE, Yang Y, Zhang M, Monahan BJ, Voss AK, Thomas T, Street IP, Dawson SJ, Dawson MA, Lindeman GJ, Davis MJ, Visvader JE, Paul TA. Sharma S, et al. Among authors: white kl. Cell Chem Biol. 2023 Oct 19;30(10):1191-1210.e20. doi: 10.1016/j.chembiol.2023.07.005. Epub 2023 Aug 8. Cell Chem Biol. 2023. PMID: 37557181 Free article.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Baell JB, Leaver DJ, Hermans SJ, Kelly GL, Brennan MS, Downer NL, Nguyen N, Wichmann J, McRae HM, Yang Y, Cleary B, Lagiakos HR, Mieruszynski S, Pacini G, Vanyai HK, Bergamasco MI, May RE, Davey BK, Morgan KJ, Sealey AJ, Wang B, Zamudio N, Wilcox S, Garnham AL, Sheikh BN, Aubrey BJ, Doggett K, Chung MC, de Silva M, Bentley J, Pilling P, Hattarki M, Dolezal O, Dennis ML, Falk H, Ren B, Charman SA, White KL, Rautela J, Newbold A, Hawkins ED, Johnstone RW, Huntington ND, Peat TS, Heath JK, Strasser A, Parker MW, Smyth GK, Street IP, Monahan BJ, Voss AK, Thomas T. Baell JB, et al. Among authors: white kl. Nature. 2018 Aug;560(7717):253-257. doi: 10.1038/s41586-018-0387-5. Epub 2018 Aug 1. Nature. 2018. PMID: 30069049
Antimalarial pyrido[1,2-a]benzimidazoles.
Ndakala AJ, Gessner RK, Gitari PW, October N, White KL, Hudson A, Fakorede F, Shackleford DM, Kaiser M, Yeates C, Charman SA, Chibale K. Ndakala AJ, et al. Among authors: white kl. J Med Chem. 2011 Jul 14;54(13):4581-9. doi: 10.1021/jm200227r. Epub 2011 Jun 16. J Med Chem. 2011. PMID: 21644541
Emergency ventilator for COVID-19.
King WP, Amos J, Azer M, Baker D, Bashir R, Best C, Bethke E, Boppart SA, Bralts E, Corey RM, Dietkus R, Durack G, Elbel S, Elliott G, Fava J, Goldenfeld N, Goldstein MH, Hayes C, Herndon N, Jamison S, Johnson B, Johnson H, Johnson M, Kolaczynski J, Lee T, Maslov S, McGregor DJ, Milner D, Moller R, Mosley J, Musser A, Newberger M, Null D, O'Bryan L, Oelze M, O'Leary J, Pagano A, Philpott M, Pianfetti B, Pille A, Pizzuto L, Ricconi B, Rubessa M, Rylowicz S, Shipley C, Singer AC, Stewart B, Switzky R, Tawfick S, Wheeler M, White K, Widloski EM, Wood E, Wood C, Wooldridge AR. King WP, et al. Among authors: white k. PLoS One. 2020 Dec 30;15(12):e0244963. doi: 10.1371/journal.pone.0244963. eCollection 2020. PLoS One. 2020. PMID: 33378363 Free PMC article.
COVID-19 Point-of-Care Diagnostics: Present and Future.
Valera E, Jankelow A, Lim J, Kindratenko V, Ganguli A, White K, Kumar J, Bashir R. Valera E, et al. Among authors: white k. ACS Nano. 2021 May 25;15(5):7899-7906. doi: 10.1021/acsnano.1c02981. Epub 2021 May 13. ACS Nano. 2021. PMID: 33984237 Free article.
Outside Our Walls: the Case for City-Wide Collaboration to Reduce Disparities.
Haas JS, Lemon SC, Freund KM, Battaglia TA; Translating Research Into Practice (TRIP) Consortium Writing Group. Haas JS, et al. J Gen Intern Med. 2021 Jan;36(1):211-213. doi: 10.1007/s11606-020-06006-7. Epub 2020 Jul 27. J Gen Intern Med. 2021. PMID: 32720235 Free PMC article. No abstract available.
Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines.
Priebbenow DL, Mathiew M, Shi DH, Harjani JR, Beveridge JG, Chavchich M, Edstein MD, Duffy S, Avery VM, Jacobs RT, Brand S, Shackleford DM, Wang W, Zhong L, Lee G, Tay E, Barker H, Crighton E, White KL, Charman SA, De Paoli A, Creek DJ, Baell JB. Priebbenow DL, et al. Among authors: white kl. J Med Chem. 2021 Apr 8;64(7):4150-4162. doi: 10.1021/acs.jmedchem.1c00044. Epub 2021 Mar 24. J Med Chem. 2021. PMID: 33759519
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1.
Braillard S, Keenan M, Breese KJ, Heppell J, Abbott M, Islam R, Shackleford DM, Katneni K, Crighton E, Chen G, Patil R, Lee G, White KL, Carvalho S, Wall RJ, Chemi G, Zuccotto F, González S, Marco M, Deakyne J, Standing D, Brunori G, Lyon JJ, Castañeda-Casado P, Camino I, Martinez Martinez MS, Zulfiqar B, Avery VM, Feijens PB, Van Pelt N, Matheeussen A, Hendrickx S, Maes L, Caljon G, Yardley V, Wyllie S, Charman SA, Chatelain E. Braillard S, et al. Among authors: white kl. Sci Transl Med. 2023 Dec 13;15(726):eadh9902. doi: 10.1126/scitranslmed.adh9902. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091406 Free PMC article.
Progress in antischistosomal N,N'-diaryl urea SAR.
Wu J, Wang C, Leas D, Vargas M, White KL, Shackleford DM, Chen G, Sanford AG, Hemsley RM, Davis PH, Dong Y, Charman SA, Keiser J, Vennerstrom JL. Wu J, et al. Among authors: white kl. Bioorg Med Chem Lett. 2018 Feb 1;28(3):244-248. doi: 10.1016/j.bmcl.2017.12.064. Epub 2017 Dec 29. Bioorg Med Chem Lett. 2018. PMID: 29317164 Free PMC article.
181 results