Christina R. Bourne - Search Results

Year	Number of Results
2003	1
2005	1
2006	2
2007	1
2009	2
2012	7
2013	2
2014	5
2015	2
2016	1
2018	1
2019	2
2020	2
2021	4
2022	3
2023	1
2024	1

1

Structure-Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4.

Severance ZC, Nuñez JI, Le-McClain AT, Malinky CA, Bensen RC, Fogle RS, Manginelli GW, Sakers SH, Falcon EC, Bui RH, Snead KJ, Bourne CR, Burgett AWG. Severance ZC, et al. Among authors: bourne cr. J Med Chem. 2023 Mar 23;66(6):3866-3875. doi: 10.1021/acs.jmedchem.2c01025. Epub 2023 Mar 14. J Med Chem. 2023. PMID: 36916802 Free PMC article.

2

Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways.

Muthuramalingam M, White JC, Bourne CR. Muthuramalingam M, et al. Among authors: bourne cr. Toxins (Basel). 2016 Jul 9;8(7):214. doi: 10.3390/toxins8070214. Toxins (Basel). 2016. PMID: 27409636 Free PMC article. Review.

3

Friend or Foe: Protein Inhibitors of DNA Gyrase.

Ruan S, Tu CH, Bourne CR. Ruan S, et al. Among authors: bourne cr. Biology (Basel). 2024 Jan 29;13(2):84. doi: 10.3390/biology13020084. Biology (Basel). 2024. PMID: 38392303 Free PMC article. Review.

4

A YoeB toxin cleaves both RNA and DNA.

McGillick J, Ames JR, Murphy T, Bourne CR. McGillick J, et al. Among authors: bourne cr. Sci Rep. 2021 Feb 11;11(1):3592. doi: 10.1038/s41598-021-82950-6. Sci Rep. 2021. PMID: 33574407 Free PMC article.

5

Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery.

Bourne CR. Bourne CR. Antibiotics (Basel). 2014 Jan 21;3(1):1-28. doi: 10.3390/antibiotics3010001. Antibiotics (Basel). 2014. PMID: 27025730 Free PMC article. Review.

6

Bacterial Growth Mindset: Structural Plasticity in Defense Systems.

Bourne CR. Bourne CR. Structure. 2021 Feb 4;29(2):97-98. doi: 10.1016/j.str.2021.01.007. Structure. 2021. PMID: 33545061 Free article.

7

Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus.

Johnson BP, Kumar V, Scull EM, Thomas LM, Bourne CR, Singh S. Johnson BP, et al. Among authors: bourne cr. ACS Chem Biol. 2022 Jan 21;17(1):85-102. doi: 10.1021/acschembio.1c00655. Epub 2021 Dec 14. ACS Chem Biol. 2022. PMID: 34905349 Free PMC article.

8

Identifying a Molecular Mechanism That Imparts Species-Specific Toxicity to YoeB Toxins.

Ames JR, McGillick J, Murphy T, Reddem E, Bourne CR. Ames JR, et al. Among authors: bourne cr. Front Microbiol. 2020 May 21;11:959. doi: 10.3389/fmicb.2020.00959. eCollection 2020. Front Microbiol. 2020. PMID: 32528435 Free PMC article.

9

Synthesis and Characterization of Functionalized Amino Dihydropyrimidines Toward the Analysis of their Antibacterial Structure-Activity Relationships and Mechanism of Action.

Boyer ZW, Kessler H, Brosman H, Ruud KJ, Falkowski AF, Viollet C, Bourne CR, O'Reilly MC. Boyer ZW, et al. Among authors: bourne cr. ACS Omega. 2022 Oct 13;7(42):37907-37916. doi: 10.1021/acsomega.2c05071. eCollection 2022 Oct 25. ACS Omega. 2022. PMID: 36312355 Free PMC article.

10

ParD Antitoxin Hotspot Alters a Disorder-to-Order Transition upon Binding to Its Cognate ParE Toxin, Lessening Its Interaction Affinity and Increasing Its Protease Degradation Kinetics.

Snead KJ, Moore LL, Bourne CR. Snead KJ, et al. Among authors: bourne cr. Biochemistry. 2022 Jan 4;61(1):34-45. doi: 10.1021/acs.biochem.1c00584. Epub 2021 Dec 16. Biochemistry. 2022. PMID: 34914378 Free PMC article.

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