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Showing results for A. B. chop
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Investigating interactions between phospholipase B-Like 2 and antibodies during Protein A chromatography.
Tran B, Grosskopf V, Wang X, Yang J, Walker D Jr, Yu C, McDonald P. Tran B, et al. J Chromatogr A. 2016 Mar 18;1438:31-8. doi: 10.1016/j.chroma.2016.01.047. Epub 2016 Jan 22. J Chromatogr A. 2016. PMID: 26896920
While the majority of host-cell proteins are cleared through purification processes, individual host-cell proteins such as Phospholipase B-like 2 (PLBL2) are more challenging to remove and can persist into the final purification pool even after multiple chromatography step …
While the majority of host-cell proteins are cleared through purification processes, individual host-cell proteins such as Phospholipase …
Resveratrol Alleviates Inflammation and ER Stress Through SIRT1/NRF2 to Delay Ovarian Aging in a Short-Lived Fish.
Zhu H, Li X, Qiao M, Sun X, Li G. Zhu H, et al. J Gerontol A Biol Sci Med Sci. 2023 Mar 30;78(4):596-602. doi: 10.1093/gerona/glad009. J Gerontol A Biol Sci Med Sci. 2023. PMID: 36630695
Moreover, the expression of SIRT1 and NRF2 decreased and the levels of NF-kappaB, pro-inflammatory cytokines IL-1beta, TNF-alpha, and IL-8 and endoplasmic reticulum (ER) stress markers GRP78 and CHOP increased with aging, while resveratrol up-regulated SIRT1 and NRF2 expre …
Moreover, the expression of SIRT1 and NRF2 decreased and the levels of NF-kappaB, pro-inflammatory cytokines IL-1beta, TNF-alpha, and IL-8 a …
Inefficient V(D)J recombination underlies monogenic T cell receptor β expression.
Wu GS, Bassing CH. Wu GS, et al. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18172-18174. doi: 10.1073/pnas.2010077117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690689 Free PMC article.
At most AgR loci, V(D)J recombination is regulated so that only one allele assembles a functional gene, ensuring that nearly every T and B cell expresses a single type, or specificity, of AgR. The genomic organizations of some AgR loci permit the assembly and expression of …
At most AgR loci, V(D)J recombination is regulated so that only one allele assembles a functional gene, ensuring that nearly every T and …
TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Wang Y, Su L, Morin MD, Jones BT, Whitby LR, Surakattula MM, Huang H, Shi H, Choi JH, Wang KW, Moresco EM, Berger M, Zhan X, Zhang H, Boger DL, Beutler B. Wang Y, et al. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E884-93. doi: 10.1073/pnas.1525639113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831104 Free PMC article.
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression.
Fishbein A, Wang W, Yang H, Yang J, Hallisey VM, Deng J, Verheul SML, Hwang SH, Gartung A, Wang Y, Bielenberg DR, Huang S, Kieran MW, Hammock BD, Panigrahy D. Fishbein A, et al. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21576-21587. doi: 10.1073/pnas.2007412117. Epub 2020 Aug 14. Proc Natl Acad Sci U S A. 2020. PMID: 32801214 Free PMC article.
While eicosanoid and cytokine storms are well-characterized in infection and inflammation, they are poorly characterized in cancer. Here, we demonstrate that carcinogens, such as aflatoxin B(1) (AFB(1)), induce apoptotic cell death and the resulting cell debris stimulates …
While eicosanoid and cytokine storms are well-characterized in infection and inflammation, they are poorly characterized in cancer. Here, we …
[B-cell lymphoma of the testes].
Zugor V, Frank M, Krause FS, Schott GE, Aigner T, Engehausen DG. Zugor V, et al. Urologe A. 2006 Oct;45(10):1308-11. doi: 10.1007/s00120-006-1081-z. Urologe A. 2006. PMID: 16788784 German.
The standard chemotherapy for aggressive non-Hodgkin's lymphomas is the CHOP regimen consisting of cyclophosphamide, doxorubicin, vincristine, and prednisone. This article presents two adults aged 67 and 75 years with histologically proven B-cell lymphoma of the tes …
The standard chemotherapy for aggressive non-Hodgkin's lymphomas is the CHOP regimen consisting of cyclophosphamide, doxorubicin, vin …
BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress.
Carpio MA, Michaud M, Zhou W, Fisher JK, Walensky LD, Katz SG. Carpio MA, et al. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7201-6. doi: 10.1073/pnas.1421063112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26015568 Free PMC article.
B-cell lymphoma 2 (BCL-2) ovarian killer (BOK) is a BCL-2 family protein with high homology to the multidomain proapoptotic proteins BAX and BAK, yet Bok(-/-) and even Bax(-/-)Bok(-/-) and Bak(-/-)Bok(-/-) mice were reported to have no overt phenotype or apoptotic defects …
B-cell lymphoma 2 (BCL-2) ovarian killer (BOK) is a BCL-2 family protein with high homology to the multidomain proapoptotic proteins …
Cloning of a receptor for amphibian [Phe13]bombesin distinct from the receptor for gastrin-releasing peptide: identification of a fourth bombesin receptor subtype (BB4).
Nagalla SR, Barry BJ, Creswick KC, Eden P, Taylor JT, Spindel ER. Nagalla SR, et al. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):6205-9. doi: 10.1073/pnas.92.13.6205. Proc Natl Acad Sci U S A. 1995. PMID: 7597102 Free PMC article.
The relative rank potency of bombesin-like peptides for this receptor was [Phe13]bombesin > [Leu13]bombesin > GRP > neuromedin B. In contrast, the rank potency for the GRP receptor is GRP > [Leu13]bombesin > [Phe13]bombesin > neuromedin B. Transien …
The relative rank potency of bombesin-like peptides for this receptor was [Phe13]bombesin > [Leu13]bombesin > GRP > neuromedin B …
Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress.
Salah A, Bouaziz C, Prola A, Pires Da Silva J, Bacha H, Abid-Essefi S, Lemaire C. Salah A, et al. J Toxicol Environ Health A. 2017;80(23-24):1230-1241. doi: 10.1080/15287394.2017.1359127. J Toxicol Environ Health A. 2017. PMID: 29165056
It was also found that CTN triggered endoplasmic reticulum (ER) stress and activated different arms of the unfolded protein response (UPR) as demonstrated by increase in expression of GRP78 (glucose-regulated protein-78), GRP94 (glucose-regulated protein-94), GADD34 (growth arres …
It was also found that CTN triggered endoplasmic reticulum (ER) stress and activated different arms of the unfolded protein response (UPR) a …
11 results