Marshall GR - Search Results

1

Second-generation benzodiazepine CCK-B antagonists. Development of subnanomolar analogs with selectivity and water solubility.

Bock MG, DiPardo RM, Mellin EC, Newton RC, Veber DF, Freedman SB, Smith AJ, Patel S, Kemp JA, Marshall GR, et al. Bock MG, et al. Among authors: marshall gr. J Med Chem. 1994 Mar 18;37(6):722-4. doi: 10.1021/jm00032a003. J Med Chem. 1994. PMID: 8145220 Review. No abstract available.

2

High-affinity and potent, water-soluble 5-amino-1,4-benzodiazepine CCKB/gastrin receptor antagonists containing a cationic solubilizing group.

Showell GA, Bourrain S, Neduvelil JG, Fletcher SR, Baker R, Watt AP, Fletcher AE, Freedman SB, Kemp JA, Marshall GR. Showell GA, et al. Among authors: marshall gr. J Med Chem. 1994 Mar 18;37(6):719-21. doi: 10.1021/jm00032a002. J Med Chem. 1994. PMID: 8145219 Review. No abstract available.

3

A second generation of non-peptide cholecystokinin receptor antagonists and their possible therapeutic potential.

Freedman SB, Patel S, Smith AJ, Chapman K, Fletcher A, Kemp JA, Marshall GR, Hargreaves RJ, Scholey K, Mellin EC, et al. Freedman SB, et al. Among authors: marshall gr. Ann N Y Acad Sci. 1994 Mar 23;713:312-8. doi: 10.1111/j.1749-6632.1994.tb44079.x. Ann N Y Acad Sci. 1994. PMID: 8185173 Review.

4

5-(Piperidin-2-yl)- and 5-(homopiperidin-2-yl)-1,4-benzodiazepines: high-affinity, basic ligands for the cholecystokinin-B receptor.

Castro JL, Broughton HB, Russell MG, Rathbone D, Watt AP, Ball RG, Chapman KL, Patel S, Smith AJ, Marshall GR, Matassa VG. Castro JL, et al. Among authors: marshall gr. J Med Chem. 1997 Aug 1;40(16):2491-501. doi: 10.1021/jm9608523. J Med Chem. 1997. PMID: 9258356

5

2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor.

Carling RW, Leeson PD, Moseley AM, Baker R, Foster AC, Grimwood S, Kemp JA, Marshall GR. Carling RW, et al. Among authors: marshall gr. J Med Chem. 1992 May 29;35(11):1942-53. doi: 10.1021/jm00089a003. J Med Chem. 1992. PMID: 1534583

6

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor.

Leeson PD, Baker R, Carling RW, Curtis NR, Moore KW, Williams BJ, Foster AC, Donald AE, Kemp JA, Marshall GR. Leeson PD, et al. Among authors: marshall gr. J Med Chem. 1991 Apr;34(4):1243-52. doi: 10.1021/jm00108a002. J Med Chem. 1991. PMID: 1826744

7

Structure and activity of hydrogenated derivatives of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801).

Lyle TA, Magill CA, Britcher SF, Denny GH, Thompson WJ, Murphy JS, Knight AR, Kemp JA, Marshall GR, Middlemiss DN, et al. Lyle TA, et al. Among authors: marshall gr. J Med Chem. 1990 Mar;33(3):1047-52. doi: 10.1021/jm00165a026. J Med Chem. 1990. PMID: 2155319

8

Biological properties of the benzodiazepine amidine derivative L-740,093, a cholecystokinin-B/gastrin receptor antagonist with high affinity in vitro and high potency in vivo.

Patel S, Smith AJ, Chapman KL, Fletcher AE, Kemp JA, Marshall GR, Hargreaves RJ, Ryecroft W, Iversen LL, Iversen SD, et al. Patel S, et al. Among authors: marshall gr. Mol Pharmacol. 1994 Nov;46(5):943-8. Mol Pharmacol. 1994. PMID: 7969084

9

3-Acyl-4-hydroxyquinolin-2(1H)-ones. Systemically active anticonvulsants acting by antagonism at the glycine site of the N-methyl-D-aspartate receptor complex.

Rowley M, Leeson PD, Stevenson GI, Moseley AM, Stansfield I, Sanderson I, Robinson L, Baker R, Kemp JA, Marshall GR, et al. Rowley M, et al. Among authors: marshall gr. J Med Chem. 1993 Oct 29;36(22):3386-96. doi: 10.1021/jm00074a020. J Med Chem. 1993. PMID: 8230129

10

4-substituted-3-phenylquinolin-2(1H)-ones: acidic and nonacidic glycine site N-methyl-D-aspartate antagonists with in vivo activity.

Carling RW, Leeson PD, Moore KW, Moyes CR, Duncton M, Hudson ML, Baker R, Foster AC, Grimwood S, Kemp JA, Marshall GR, Tricklebank MD, Saywell KL. Carling RW, et al. Among authors: marshall gr. J Med Chem. 1997 Feb 28;40(5):754-65. doi: 10.1021/jm9605492. J Med Chem. 1997. PMID: 9057862

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