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Exploring the targeting spectrum of rocaglates among eIF4A homologs.
Naineni SK, Cencic R, Robert F, Brown LE, Haque M, Scott-Talib J, Sénéchal P, Schmeing TM, Porco JA Jr, Pelletier J. Naineni SK, et al. Among authors: brown le. RNA. 2023 Jun;29(6):826-835. doi: 10.1261/rna.079318.122. Epub 2023 Mar 7. RNA. 2023. PMID: 36882295 Free PMC article.
Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors.
Chu J, Zhang W, Cencic R, Devine WG, Beglov D, Henkel T, Brown LE, Vajda S, Porco JA Jr, Pelletier J. Chu J, et al. Among authors: brown le. Cell Chem Biol. 2019 Nov 21;26(11):1586-1593.e3. doi: 10.1016/j.chembiol.2019.08.008. Epub 2019 Sep 10. Cell Chem Biol. 2019. PMID: 31519508 Free PMC article.
Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation.
Itoua Maïga R, Cencic R, Chu J, Waller DD, Brown LE, Devine WG, Zhang W, Sebag M, Porco JA Jr, Pelletier J. Itoua Maïga R, et al. Among authors: brown le. Sci Rep. 2019 Feb 4;9(1):1265. doi: 10.1038/s41598-018-37666-5. Sci Rep. 2019. PMID: 30718665 Free PMC article.
Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F.
Chu J, Zhang W, Cencic R, O'Connor PBF, Robert F, Devine WG, Selznick A, Henkel T, Merrick WC, Brown LE, Baranov PV, Porco JA Jr, Pelletier J. Chu J, et al. Among authors: brown le. Cell Rep. 2020 Feb 25;30(8):2481-2488.e5. doi: 10.1016/j.celrep.2020.02.002. Cell Rep. 2020. PMID: 32101697 Free PMC article.
Rocaglates as dual-targeting agents for experimental cerebral malaria.
Langlais D, Cencic R, Moradin N, Kennedy JM, Ayi K, Brown LE, Crandall I, Tarry MJ, Schmeing M, Kain KC, Porco JA Jr, Pelletier J, Gros P. Langlais D, et al. Among authors: brown le. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2366-E2375. doi: 10.1073/pnas.1713000115. Epub 2018 Feb 20. Proc Natl Acad Sci U S A. 2018. PMID: 29463745 Free PMC article.
537 results