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Membrane to cortex attachment determines different mechanical phenotypes in LGR5+ and LGR5- colorectal cancer cells.
Nat Commun. 2024 Apr 18;15(1):3363. doi: 10.1038/s41467-024-47227-2.
Nat Commun. 2024.
PMID: 38637494
Free PMC article.
Antitumor T-cell function requires CPEB4-mediated adaptation to chronic endoplasmic reticulum stress.
Fernández-Alfara M, Sibilio A, Martin J, Tusquets Uxó E, Malumbres M, Alcalde V, Chanes V, Cañellas-Socias A, Palomo-Ponce S, Batlle E, Méndez R.
Fernández-Alfara M, et al. Among authors: canellas socias a.
EMBO J. 2023 May 2;42(9):e111494. doi: 10.15252/embj.2022111494. Epub 2023 Mar 15.
EMBO J. 2023.
PMID: 36919984
Free PMC article.
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Long-term platinum-based drug accumulation in cancer-associated fibroblasts promotes colorectal cancer progression and resistance to therapy.
Linares J, Sallent-Aragay A, Badia-Ramentol J, Recort-Bascuas A, Méndez A, Manero-Rupérez N, Re DL, Rivas EI, Guiu M, Zwick M, Iglesias M, Martinez-Ciarpaglini C, Tarazona N, Varese M, Hernando-Momblona X, Cañellas-Socias A, Orrillo M, Garrido M, Saoudi N, Elez E, Navarro P, Tabernero J, Gomis RR, Batlle E, Pisonero J, Cervantes A, Montagut C, Calon A.
Linares J, et al. Among authors: canellas socias a.
Nat Commun. 2023 Feb 10;14(1):746. doi: 10.1038/s41467-023-36334-1.
Nat Commun. 2023.
PMID: 36765091
Free PMC article.
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Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.
Cañellas-Socias A, Cortina C, Hernando-Momblona X, Palomo-Ponce S, Mulholland EJ, Turon G, Mateo L, Conti S, Roman O, Sevillano M, Slebe F, Stork D, Caballé-Mestres A, Berenguer-Llergo A, Álvarez-Varela A, Fenderico N, Novellasdemunt L, Jiménez-Gracia L, Sipka T, Bardia L, Lorden P, Colombelli J, Heyn H, Trepat X, Tejpar S, Sancho E, Tauriello DVF, Leedham S, Attolini CS, Batlle E.
Cañellas-Socias A, et al.
Nature. 2022 Nov;611(7936):603-613. doi: 10.1038/s41586-022-05402-9. Epub 2022 Nov 9.
Nature. 2022.
PMID: 36352230
Free article.
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Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters.
Robles-Rebollo I, Cuartero S, Canellas-Socias A, Wells S, Karimi MM, Mereu E, Chivu AG, Heyn H, Whilding C, Dormann D, Marguerat S, Rioja I, Prinjha RK, Stumpf MPH, Fisher AG, Merkenschlager M.
Robles-Rebollo I, et al. Among authors: canellas socias a.
Nat Commun. 2022 Jul 27;13(1):4342. doi: 10.1038/s41467-022-31192-9.
Nat Commun. 2022.
PMID: 35896525
Free PMC article.
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Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy.
Álvarez-Varela A, Novellasdemunt L, Barriga FM, Hernando-Momblona X, Cañellas-Socias A, Cano-Crespo S, Sevillano M, Cortina C, Stork D, Morral C, Turon G, Slebe F, Jiménez-Gracia L, Caratù G, Jung P, Stassi G, Heyn H, Tauriello DVF, Mateo L, Tejpar S, Sancho E, Stephan-Otto Attolini C, Batlle E.
Álvarez-Varela A, et al. Among authors: canellas socias a.
Nat Cancer. 2022 Sep;3(9):1052-1070. doi: 10.1038/s43018-022-00402-0. Epub 2022 Jun 30.
Nat Cancer. 2022.
PMID: 35773527
Free article.
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Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.
Herpers B, Eppink B, James MI, Cortina C, Cañellas-Socias A, Boj SF, Hernando-Momblona X, Glodzik D, Roovers RC, van de Wetering M, Bartelink-Clements C, Zondag-van der Zande V, Mateos JG, Yan K, Salinaro L, Basmeleh A, Fatrai S, Maussang D, Lammerts van Bueren JJ, Chicote I, Serna G, Cabellos L, Ramírez L, Nuciforo P, Salazar R, Santos C, Villanueva A, Stephan-Otto Attolini C, Sancho E, Palmer HG, Tabernero J, Stratton MR, de Kruif J, Logtenberg T, Clevers H, Price LS, Vries RGJ, Batlle E, Throsby M.
Herpers B, et al. Among authors: canellas socias a.
Nat Cancer. 2022 Apr;3(4):418-436. doi: 10.1038/s43018-022-00359-0. Epub 2022 Apr 25.
Nat Cancer. 2022.
PMID: 35469014
Free article.
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