Li J - Search Results

1

Discovery of novel Thymol-TPP antibiotics that eradicate MRSA persisters.

Tang Z, Feng J, Challa M, Rowthu SR, Xiong S, Zou C, Li J, Verma CS, Peng H, He X, Huang C, He Y. Tang Z, et al. Among authors: li j. Eur J Med Chem. 2024 Apr 15;270:116381. doi: 10.1016/j.ejmech.2024.116381. Epub 2024 Apr 3. Eur J Med Chem. 2024. PMID: 38604097

2

Symmetrically Substituted Xanthone Amphiphiles Combat Gram-Positive Bacterial Resistance with Enhanced Membrane Selectivity.

Lin S, Koh JJ, Aung TT, Lim F, Li J, Zou H, Wang L, Lakshminarayanan R, Verma C, Wang Y, Tan DT, Cao D, Beuerman RW, Ren L, Liu S. Lin S, et al. Among authors: li j. J Med Chem. 2017 Feb 23;60(4):1362-1378. doi: 10.1021/acs.jmedchem.6b01403. Epub 2017 Feb 13. J Med Chem. 2017. PMID: 28122182

3

Design and evaluation of tadpole-like conformational antimicrobial peptides.

Tang Z, Jiang W, Li S, Huang X, Yang Y, Chen X, Qiu J, Xiao C, Xie Y, Zhang X, Li J, Verma CS, He Y, Yang A. Tang Z, et al. Among authors: li s, li j. Commun Biol. 2023 Nov 18;6(1):1177. doi: 10.1038/s42003-023-05560-0. Commun Biol. 2023. PMID: 37980400 Free PMC article.

4

Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity.

Zou H, Koh JJ, Li J, Qiu S, Aung TT, Lin H, Lakshminarayanan R, Dai X, Tang C, Lim FH, Zhou L, Tan AL, Verma C, Tan DT, Chan HS, Saraswathi P, Cao D, Liu S, Beuerman RW. Zou H, et al. Among authors: li j. J Med Chem. 2013 Mar 28;56(6):2359-73. doi: 10.1021/jm301683j. Epub 2013 Mar 13. J Med Chem. 2013. PMID: 23441632

5

Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections.

Koh JJ, Lin S, Aung TT, Lim F, Zou H, Bai Y, Li J, Lin H, Pang LM, Koh WL, Salleh SM, Lakshminarayanan R, Zhou L, Qiu S, Pervushin K, Verma C, Tan DT, Cao D, Liu S, Beuerman RW. Koh JJ, et al. Among authors: li j. J Med Chem. 2015 Jan 22;58(2):739-52. doi: 10.1021/jm501285x. Epub 2014 Dec 17. J Med Chem. 2015. PMID: 25474410

6

N-Lipidated Peptide Dimers: Effective Antibacterial Agents against Gram-Negative Pathogens through Lipopolysaccharide Permeabilization.

Koh JJ, Lin H, Caroline V, Chew YS, Pang LM, Aung TT, Li J, Lakshminarayanan R, Tan DT, Verma C, Tan AL, Beuerman RW, Liu S. Koh JJ, et al. Among authors: li j. J Med Chem. 2015 Aug 27;58(16):6533-48. doi: 10.1021/acs.jmedchem.5b00628. Epub 2015 Aug 12. J Med Chem. 2015. PMID: 26214729

7

Nonpeptidic Amphiphilic Xanthone Derivatives: Structure-Activity Relationship and Membrane-Targeting Properties.

Koh JJ, Zou H, Lin S, Lin H, Soh RT, Lim FH, Koh WL, Li J, Lakshminarayanan R, Verma C, Tan DT, Cao D, Beuerman RW, Liu S. Koh JJ, et al. Among authors: li j. J Med Chem. 2016 Jan 14;59(1):171-93. doi: 10.1021/acs.jmedchem.5b01500. Epub 2015 Dec 18. J Med Chem. 2016. PMID: 26681070

8

Molecular Environment Modulates Conformational Differences between Crystal and Solution States of Human β-Defensin 2.

Li J, Hu Z, Beuerman R, Verma C. Li J, et al. J Phys Chem B. 2017 Apr 6;121(13):2739-2747. doi: 10.1021/acs.jpcb.7b00083. Epub 2017 Mar 27. J Phys Chem B. 2017. PMID: 28294607

9

Mechanism of polyamine induced colistin resistance through electrostatic networks on bacterial outer membranes.

Li J, Beuerman R, Verma CS. Li J, et al. Biochim Biophys Acta Biomembr. 2020 Sep 1;1862(9):183297. doi: 10.1016/j.bbamem.2020.183297. Epub 2020 Apr 24. Biochim Biophys Acta Biomembr. 2020. PMID: 32339485 Free article.

10

Dissecting the Molecular Mechanism of Colistin Resistance in mcr-1 Bacteria.

Li J, Beuerman R, Verma CS. Li J, et al. J Chem Inf Model. 2020 Oct 26;60(10):4975-4984. doi: 10.1021/acs.jcim.0c01051. Epub 2020 Oct 5. J Chem Inf Model. 2020. PMID: 33017152

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