Astegno A - Search Results

1

Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria.

Al-Sadeq DW, Conter C, Thanassoulas A, Al-Dewik N, Safieh-Garabedian B, Martínez-Cruz LA, Nasrallah GK, Astegno A, Nomikos M. Al-Sadeq DW, et al. Among authors: astegno a. Biochem J. 2024 Apr 24;481(8):569-585. doi: 10.1042/BCJ20240012. Biochem J. 2024. PMID: 38563463

2

Hydrogen sulfide production does not affect antibiotic resistance in Pseudomonas aeruginosa.

Caruso L, Mellini M, Catalano Gonzaga O, Astegno A, Forte E, Di Matteo A, Giuffrè A, Visca P, Imperi F, Leoni L, Rampioni G. Caruso L, et al. Among authors: astegno a. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0007524. doi: 10.1128/aac.00075-24. Epub 2024 Mar 6. Antimicrob Agents Chemother. 2024. PMID: 38445869 Free PMC article.

3

Conformational and dynamic properties of the KH1 domain of FMRP and its fragile X syndrome linked G266E variant.

Catalano F, Santorelli D, Astegno A, Favretto F, D'Abramo M, Del Giudice A, De Sciscio ML, Troilo F, Giardina G, Di Matteo A, Travaglini-Allocatelli C. Catalano F, et al. Among authors: astegno a. Biochim Biophys Acta Proteins Proteom. 2024 Jul 1;1872(4):141019. doi: 10.1016/j.bbapap.2024.141019. Epub 2024 Apr 17. Biochim Biophys Acta Proteins Proteom. 2024. PMID: 38641086 Free article.

4

Catalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa.

Pedretti M, Fernández-Rodríguez C, Conter C, Oyenarte I, Favretto F, di Matteo A, Dominici P, Petrosino M, Martinez-Chantar ML, Majtan T, Astegno A, Martínez-Cruz LA. Pedretti M, et al. Among authors: astegno a. Sci Rep. 2024 Apr 23;14(1):9364. doi: 10.1038/s41598-024-57625-7. Sci Rep. 2024. PMID: 38654065 Free PMC article.

5

Role of myristoylation in modulating PCaP1 interaction with calmodulin.

Pedretti M, Favretto F, Troilo F, Giovannoni M, Conter C, Mattei B, Dominici P, Travaglini-Allocatelli C, Di Matteo A, Astegno A. Pedretti M, et al. Among authors: astegno a. Plant Physiol Biochem. 2023 Oct;203:108003. doi: 10.1016/j.plaphy.2023.108003. Epub 2023 Sep 9. Plant Physiol Biochem. 2023. PMID: 37717348 Free article.

6

Key substrate recognition residues in the active site of cystathionine beta-synthase from Toxoplasma gondii.

Conter C, Favretto F, Dominici P, Martinez-Cruz LA, Astegno A. Conter C, et al. Among authors: astegno a. Proteins. 2023 Oct;91(10):1383-1393. doi: 10.1002/prot.26507. Epub 2023 May 10. Proteins. 2023. PMID: 37163386

7

Structural basis of the inhibition of cystathionine γ-lyase from Toxoplasma gondii by propargylglycine and cysteine.

Fernández-Rodríguez C, Conter C, Oyenarte I, Favretto F, Quintana I, Martinez-Chantar ML, Astegno A, Martínez-Cruz LA. Fernández-Rodríguez C, et al. Among authors: astegno a. Protein Sci. 2023 Apr;32(4):e4619. doi: 10.1002/pro.4619. Protein Sci. 2023. PMID: 36883335 Free PMC article.

8

Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii.

Favretto F, Jiménez-Faraco E, Conter C, Dominici P, Hermoso JA, Astegno A. Favretto F, et al. Among authors: astegno a. ACS Infect Dis. 2023 Feb 10;9(2):365-377. doi: 10.1021/acsinfecdis.2c00566. Epub 2023 Jan 18. ACS Infect Dis. 2023. PMID: 36653744 Free PMC article.

9

Conformational Plasticity of Centrin 1 from Toxoplasma gondii in Binding to the Centrosomal Protein SFI1.

Bombardi L, Favretto F, Pedretti M, Conter C, Dominici P, Astegno A. Bombardi L, et al. Among authors: astegno a. Biomolecules. 2022 Aug 13;12(8):1115. doi: 10.3390/biom12081115. Biomolecules. 2022. PMID: 36009009 Free PMC article.

10

Insights into Domain Organization and Regulatory Mechanism of Cystathionine Beta-Synthase from Toxoplasma gondii.

Conter C, Fruncillo S, Favretto F, Fernández-Rodríguez C, Dominici P, Martínez-Cruz LA, Astegno A. Conter C, et al. Among authors: astegno a. Int J Mol Sci. 2022 Jul 25;23(15):8169. doi: 10.3390/ijms23158169. Int J Mol Sci. 2022. PMID: 35897745 Free PMC article.

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