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Polyketide synthase positive Escherichia coli one-time measurement in stool is not informative of colorectal cancer risk in a screening setting.
de Klaver W, de Wit M, Bolijn A, Tijssen M, Delis-van Diemen P, Lemmens M, Spaander MC, Dekker E, van Leerdam ME, Coupé VM, van Boxtel R, Clevers H, Carvalho B, Meijer GA. de Klaver W, et al. Among authors: clevers h. J Pathol. 2024 Jun;263(2):217-225. doi: 10.1002/path.6276. Epub 2024 Mar 29. J Pathol. 2024. PMID: 38551073
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer.
Rosendahl Huber A, Pleguezuelos-Manzano C, Puschhof J, Ubels J, Boot C, Saftien A, Verheul M, Trabut LT, Groenen N, van Roosmalen M, Ouyang KS, Wood H, Quirke P, Meijer G, Cuppen E, Clevers H, van Boxtel R. Rosendahl Huber A, et al. Among authors: clevers h. Cancer Cell. 2024 Mar 11;42(3):487-496.e6. doi: 10.1016/j.ccell.2024.02.009. Cancer Cell. 2024. PMID: 38471458 Free article.
Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.
Mertens S, Huismans MA, Verissimo CS, Ponsioen B, Overmeer R, Proost N, van Tellingen O, van de Ven M, Begthel H, Boj SF, Clevers H, Roodhart JML, Bos JL, Snippert HJG. Mertens S, et al. Among authors: clevers h. Cell Rep. 2023 Apr 25;42(4):112324. doi: 10.1016/j.celrep.2023.112324. Epub 2023 Mar 30. Cell Rep. 2023. PMID: 37000626 Free article.
Human fetal brain self-organizes into long-term expanding organoids.
Hendriks D, Pagliaro A, Andreatta F, Ma Z, van Giessen J, Massalini S, López-Iglesias C, van Son GJF, DeMartino J, Damen JMA, Zoutendijk I, Staliarova N, Bredenoord AL, Holstege FCP, Peters PJ, Margaritis T, Chuva de Sousa Lopes S, Wu W, Clevers H, Artegiani B. Hendriks D, et al. Among authors: clevers h. Cell. 2024 Feb 1;187(3):712-732.e38. doi: 10.1016/j.cell.2023.12.012. Epub 2024 Jan 8. Cell. 2024. PMID: 38194967 Free article.
822 results