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The importance of murine phospho-MLKL-S345 in situ detection for necroptosis assessment in vivo.
Kelepouras K, Saggau J, Varanda AB, Zrilic M, Kiefer C, Rakhsh-Khorshid H, Lisewski I, Uranga-Murillo I, Arias M, Pardo J, Tonnus W, Linkermann A, Annibaldi A, Walczak H, Liccardi G. Kelepouras K, et al. Among authors: saggau j. Cell Death Differ. 2024 May 23. doi: 10.1038/s41418-024-01313-6. Online ahead of print. Cell Death Differ. 2024. PMID: 38783091
CDK9 inhibition as an effective therapy for small cell lung cancer.
Valdez Capuccino L, Kleitke T, Szokol B, Svajda L, Martin F, Bonechi F, Krekó M, Azami S, Montinaro A, Wang Y, Nikolov V, Kaiser L, Bonasera D, Saggau J, Scholz T, Schmitt A, Beleggia F, Reinhardt HC, George J, Liccardi G, Walczak H, Tóvári J, Brägelmann J, Montero J, Sos ML, Őrfi L, Peltzer N. Valdez Capuccino L, et al. Among authors: saggau j. Cell Death Dis. 2024 May 20;15(5):345. doi: 10.1038/s41419-024-06724-4. Cell Death Dis. 2024. PMID: 38769311 Free PMC article.
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality.
Albert MC, Uranga-Murillo I, Arias M, De Miguel D, Peña N, Montinaro A, Varanda AB, Theobald SJ, Areso I, Saggau J, Koch M, Liccardi G, Peltzer N, Rybniker J, Hurtado-Guerrero R, Merino P, Monzón M, Badiola JJ, Reindl-Schwaighofer R, Sanz-Pamplona R, Cebollada-Solanas A, Megyesfalvi Z, Dome B, Secrier M, Hartmann B, Bergmann M, Pardo J, Walczak H. Albert MC, et al. Among authors: saggau j. Cell Death Differ. 2024 May;31(5):544-557. doi: 10.1038/s41418-024-01278-6. Epub 2024 Mar 21. Cell Death Differ. 2024. PMID: 38514848 Free PMC article.
LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1.
Vom Stein AF, Rebollido-Rios R, Lukas A, Koch M, von Lom A, Reinartz S, Bachurski D, Rose F, Bozek K, Abdallah AT, Kohlhas V, Saggau J, Zölzer R, Zhao Y, Bruns C, Bröckelmann PJ, Lohneis P, Büttner R, Häupl B, Oellerich T, Nguyen PH, Hallek M. Vom Stein AF, et al. Among authors: saggau j. Nat Commun. 2023 Mar 10;14(1):1330. doi: 10.1038/s41467-023-36824-2. Nat Commun. 2023. PMID: 36899005 Free PMC article.
Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers.
Montinaro A, Areso Zubiaur I, Saggau J, Kretz AL, Ferreira RMM, Hassan O, Kitzig E, Müller I, El-Bahrawy MA, von Karstedt S, Kulms D, Liccardi G, Lemke J, Walczak H. Montinaro A, et al. Among authors: saggau j. Cell Death Differ. 2022 Mar;29(3):492-503. doi: 10.1038/s41418-021-00869-x. Epub 2021 Sep 17. Cell Death Differ. 2022. PMID: 34535764 Free PMC article.