Harris RS - Search Results

1

Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma.

Smith NJ, Reddin I, Policelli P, Oh S, Zainal N, Howes E, Jenkins B, Tracy I, Edmond M, Sharpe B, Amendra D, Zheng K, Egawa N, Doorbar J, Rao A, Mahadevan S, Carpenter MA, Harris RS, Ali S, Hanley C, Buisson R, King E, Thomas GJ, Fenton TR. Smith NJ, et al. Among authors: harris rs. Res Sq [Preprint]. 2024 Mar 4:rs.3.rs-3997426. doi: 10.21203/rs.3.rs-3997426/v1. Res Sq. 2024. PMID: 38496447 Free PMC article. Preprint.

2

Endogenous APOBEC3A DNA cytosine deaminase is cytoplasmic and nongenotoxic.

Land AM, Law EK, Carpenter MA, Lackey L, Brown WL, Harris RS. Land AM, et al. Among authors: harris rs. J Biol Chem. 2013 Jun 14;288(24):17253-60. doi: 10.1074/jbc.M113.458661. Epub 2013 May 2. J Biol Chem. 2013. PMID: 23640892 Free PMC article.

3

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer.

Baker SC, Mason AS, Slip RG, Skinner KT, Macdonald A, Masood O, Harris RS, Fenton TR, Periyasamy M, Ali S, Southgate J. Baker SC, et al. Among authors: harris rs. Oncogene. 2022 Apr;41(15):2139-2151. doi: 10.1038/s41388-022-02235-8. Epub 2022 Feb 22. Oncogene. 2022. PMID: 35194151 Free PMC article.

4

Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage.

Wick C, Moghadasi SA, Becker JT, Fanunza E, Oh S, Bournique E, Buisson R, Harris RS. Wick C, et al. Among authors: harris rs. J Biol Chem. 2023 Sep;299(9):105073. doi: 10.1016/j.jbc.2023.105073. Epub 2023 Jul 19. J Biol Chem. 2023. PMID: 37474103 Free PMC article.

5

Mesoscale DNA Features Impact APOBEC3A and APOBEC3B Deaminase Activity and Shape Tumor Mutational Landscapes.

Sanchez A, Ortega P, Sakhtemani R, Manjunath L, Oh S, Bournique E, Becker A, Kim K, Durfee C, Temiz NA, Chen XS, Harris RS, Lawrence MS, Buisson R. Sanchez A, et al. Among authors: harris rs. bioRxiv [Preprint]. 2023 Aug 2:2023.08.02.551499. doi: 10.1101/2023.08.02.551499. bioRxiv. 2023. PMID: 37577509 Free PMC article. Updated. Preprint.

6

Deaminase deluge yields new opportunities for biotechnology and genome engineering.

Harris RS, Carpenter MA. Harris RS, et al. Mol Cell. 2024 Mar 7;84(5):816-818. doi: 10.1016/j.molcel.2024.02.016. Mol Cell. 2024. PMID: 38458171

7

Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes.

Sanchez A, Ortega P, Sakhtemani R, Manjunath L, Oh S, Bournique E, Becker A, Kim K, Durfee C, Temiz NA, Chen XS, Harris RS, Lawrence MS, Buisson R. Sanchez A, et al. Among authors: harris rs. Nat Commun. 2024 Mar 18;15(1):2370. doi: 10.1038/s41467-024-45909-5. Nat Commun. 2024. PMID: 38499542 Free PMC article.

8

A real-time biochemical assay for quantitative analyses of APOBEC-catalyzed DNA deamination.

Belica CA, Carpenter MA, Chen Y, Brown WL, Moeller NH, Boylan IT, Harris RS, Aihara H. Belica CA, et al. Among authors: harris rs. bioRxiv [Preprint]. 2024 May 12:2024.05.11.593688. doi: 10.1101/2024.05.11.593688. bioRxiv. 2024. PMID: 38766133 Free PMC article. Preprint.

9

Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A.

Carpenter MA, Li M, Rathore A, Lackey L, Law EK, Land AM, Leonard B, Shandilya SM, Bohn MF, Schiffer CA, Brown WL, Harris RS. Carpenter MA, et al. Among authors: harris rs. J Biol Chem. 2012 Oct 5;287(41):34801-8. doi: 10.1074/jbc.M112.385161. Epub 2012 Aug 15. J Biol Chem. 2012. PMID: 22896697 Free PMC article.

10

Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.

Shi K, Carpenter MA, Kurahashi K, Harris RS, Aihara H. Shi K, et al. Among authors: harris rs. J Biol Chem. 2015 Nov 20;290(47):28120-28130. doi: 10.1074/jbc.M115.679951. Epub 2015 Sep 28. J Biol Chem. 2015. PMID: 26416889 Free PMC article.

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