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Page 1
Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor.
Kesteleyn B, Bonfanti JF, Bardiot D, De Boeck B, Goethals O, Kaptein SJF, Stoops B, Coesemans E, Fortin J, Muller P, Doublet F, Carlens G, Koukni M, Smets W, Raboisson P, Chaltin P, Simmen K, Loock MV, Neyts J, Marchand A, Jonckers THM. Kesteleyn B, et al. Among authors: smets w. J Med Chem. 2024 Mar 14;67(5):4063-4082. doi: 10.1021/acs.jmedchem.3c02336. Epub 2024 Feb 28. J Med Chem. 2024. PMID: 38482827
Discovery of Indole Derivatives as Novel and Potent Dengue Virus Inhibitors.
Bardiot D, Koukni M, Smets W, Carlens G, McNaughton M, Kaptein S, Dallmeier K, Chaltin P, Neyts J, Marchand A. Bardiot D, et al. Among authors: smets w. J Med Chem. 2018 Sep 27;61(18):8390-8401. doi: 10.1021/acs.jmedchem.8b00913. Epub 2018 Sep 12. J Med Chem. 2018. PMID: 30149709
Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors.
Kesteleyn B, Bardiot D, Bonfanti JF, De Boeck B, Goethals O, Kaptein SJF, Stoops B, Coesemans E, Fortin J, Muller P, Doublet F, Carlens G, Koukni M, Smets W, Raboisson P, Chaltin P, Simmen K, Van Loock M, Neyts J, Marchand A, Jonckers THM. Kesteleyn B, et al. Among authors: smets w. J Med Chem. 2023 Jul 13;66(13):8808-8821. doi: 10.1021/acs.jmedchem.3c00403. Epub 2023 Jun 30. J Med Chem. 2023. PMID: 37389813
A Novel Irreversible TEAD Inhibitor, SWTX-143, Blocks Hippo Pathway Transcriptional Output and Causes Tumor Regression in Preclinical Mesothelioma Models.
Hillen H, Candi A, Vanderhoydonck B, Kowalczyk W, Sansores-Garcia L, Kesikiadou EC, Van Huffel L, Spiessens L, Nijs M, Soons E, Haeck W, Klaassen H, Smets W, Spieser SA, Marchand A, Chaltin P, Ciesielski F, Debaene F, Chen L, Kamal A, Gwaltney SL, Versele M, Halder GA. Hillen H, et al. Among authors: smets w. Mol Cancer Ther. 2024 Jan 3;23(1):3-13. doi: 10.1158/1535-7163.MCT-22-0681. Mol Cancer Ther. 2024. PMID: 37748190
Small-molecule inhibitors of the LEDGF/p75 binding site of integrase block HIV replication and modulate integrase multimerization.
Christ F, Shaw S, Demeulemeester J, Desimmie BA, Marchand A, Butler S, Smets W, Chaltin P, Westby M, Debyser Z, Pickford C. Christ F, et al. Among authors: smets w. Antimicrob Agents Chemother. 2012 Aug;56(8):4365-74. doi: 10.1128/AAC.00717-12. Epub 2012 Jun 4. Antimicrob Agents Chemother. 2012. PMID: 22664975 Free PMC article.
Phyllosphere bacterial communities in urban green areas throughout Europe relate to urban intensity.
Muyshondt B, Wuyts K, Van Mensel A, Smets W, Lebeer S, Aleixo C, Alós Ortí M, Casanelles-Abella J, Chiron F, Giacomo P, Laanisto L, Moretti M, Niinemets Ü, Pinho P, Tryjanowski P, Woszczyło P, Samson R. Muyshondt B, et al. Among authors: smets w. FEMS Microbiol Ecol. 2022 Sep 24;98(10):fiac106. doi: 10.1093/femsec/fiac106. FEMS Microbiol Ecol. 2022. PMID: 36085374
51 results