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Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli.
Phan MD, Nhu NTK, Achard MES, Forde BM, Hong KW, Chong TM, Yin WF, Chan KG, West NP, Walker MJ, Paterson DL, Beatson SA, Schembri MA. Phan MD, et al. Among authors: achard mes. J Antimicrob Chemother. 2017 Oct 1;72(10):2729-2736. doi: 10.1093/jac/dkx204. J Antimicrob Chemother. 2017. PMID: 29091192
Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination.
Stocks CJ, Phan MD, Achard MES, Nhu NTK, Condon ND, Gawthorne JA, Lo AW, Peters KM, McEwan AG, Kapetanovic R, Schembri MA, Sweet MJ. Stocks CJ, et al. Among authors: achard mes. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6341-6350. doi: 10.1073/pnas.1820870116. Epub 2019 Mar 7. Proc Natl Acad Sci U S A. 2019. PMID: 30846555 Free PMC article.
Copper Ions and Coordination Complexes as Novel Carbapenem Adjuvants.
Djoko KY, Achard MES, Phan MD, Lo AW, Miraula M, Prombhul S, Hancock SJ, Peters KM, Sidjabat HE, Harris PN, Mitić N, Walsh TR, Anderson GJ, Shafer WM, Paterson DL, Schenk G, McEwan AG, Schembri MA. Djoko KY, et al. Among authors: achard mes. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e02280-17. doi: 10.1128/AAC.02280-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29133551 Free PMC article.
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