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Metabolic function of autophagy is essential for cell survival.
Sedlackova L, Kataura T, Sarkar S, Korolchuk VI. Sedlackova L, et al. Among authors: korolchuk vi. Autophagy. 2023 Aug;19(8):2395-2397. doi: 10.1080/15548627.2023.2165753. Epub 2023 Feb 1. Autophagy. 2023. PMID: 36727253 Free PMC article.
The autophagy-NAD axis in longevity and disease.
Wilson N, Kataura T, Korsgen ME, Sun C, Sarkar S, Korolchuk VI. Wilson N, et al. Among authors: korolchuk vi. Trends Cell Biol. 2023 Sep;33(9):788-802. doi: 10.1016/j.tcb.2023.02.004. Epub 2023 Mar 5. Trends Cell Biol. 2023. PMID: 36878731 Free article. Review.
NDP52 acts as a redox sensor in PINK1/Parkin-mediated mitophagy.
Kataura T, Otten EG, Rabanal-Ruiz Y, Adriaenssens E, Urselli F, Scialo F, Fan L, Smith GR, Dawson WM, Chen X, Yue WW, Bronowska AK, Carroll B, Martens S, Lazarou M, Korolchuk VI. Kataura T, et al. Among authors: korolchuk vi. EMBO J. 2023 Mar 1;42(5):e111372. doi: 10.15252/embj.2022111372. Epub 2022 Dec 14. EMBO J. 2023. PMID: 36514953 Free PMC article.
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
Sun C, Seranova E, Cohen MA, Chipara M, Roberts J, Astuti D, Palhegyi AM, Acharjee A, Sedlackova L, Kataura T, Otten EG, Panda PK, Lara-Reyna S, Korsgen ME, Kauffman KJ, Huerta-Uribe A, Zatyka M, Silva LFSE, Torresi J, Zhang S, Hughes GW, Ward C, Kuechler ER, Cartwright D, Trushin S, Trushina E, Sahay G, Buganim Y, Lavery GG, Gsponer J, Anderson DG, Frickel EM, Rosenstock TR, Barrett T, Maddocks ODK, Tennant DA, Wang H, Jaenisch R, Korolchuk VI, Sarkar S. Sun C, et al. Among authors: korolchuk vi. Cell Rep. 2023 May 30;42(5):112372. doi: 10.1016/j.celrep.2023.112372. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37086404 Free PMC article.
Autophagy promotes cell survival by maintaining NAD levels.
Kataura T, Sedlackova L, Otten EG, Kumari R, Shapira D, Scialo F, Stefanatos R, Ishikawa KI, Kelly G, Seranova E, Sun C, Maetzel D, Kenneth N, Trushin S, Zhang T, Trushina E, Bascom CC, Tasseff R, Isfort RJ, Oblong JE, Miwa S, Lazarou M, Jaenisch R, Imoto M, Saiki S, Papamichos-Chronakis M, Manjithaya R, Maddocks ODK, Sanz A, Sarkar S, Korolchuk VI. Kataura T, et al. Among authors: korolchuk vi. Dev Cell. 2022 Nov 21;57(22):2584-2598.e11. doi: 10.1016/j.devcel.2022.10.008. Dev Cell. 2022. PMID: 36413951 Free article.
The pROS of Autophagy in Neuronal Health.
Sedlackova L, Kelly G, Korolchuk VI. Sedlackova L, et al. Among authors: korolchuk vi. J Mol Biol. 2020 Apr 3;432(8):2546-2559. doi: 10.1016/j.jmb.2020.01.020. Epub 2020 Jan 30. J Mol Biol. 2020. PMID: 32006535 Free PMC article. Review.
mTORC1 as the main gateway to autophagy.
Rabanal-Ruiz Y, Otten EG, Korolchuk VI. Rabanal-Ruiz Y, et al. Among authors: korolchuk vi. Essays Biochem. 2017 Dec 12;61(6):565-584. doi: 10.1042/EBC20170027. Print 2017 Dec 12. Essays Biochem. 2017. PMID: 29233869 Free PMC article. Review.
Autophagy in Neurodegenerative Diseases.
Korolchuk VI, Sarkar S, Fanto M. Korolchuk VI, et al. J Mol Biol. 2020 Apr 3;432(8):2445-2448. doi: 10.1016/j.jmb.2020.03.005. Epub 2020 Mar 10. J Mol Biol. 2020. PMID: 32169483 No abstract available.
Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells.
Vucicevic L, Misirkic M, Ciric D, Martinovic T, Jovanovic M, Isakovic A, Markovic I, Saponjic J, Foretz M, Rabanal-Ruiz Y, Korolchuk VI, Trajkovic V. Vucicevic L, et al. Among authors: korolchuk vi. Cell Mol Life Sci. 2020 Sep;77(17):3383-3399. doi: 10.1007/s00018-019-03356-2. Epub 2019 Nov 12. Cell Mol Life Sci. 2020. PMID: 31720741 Free PMC article.
87 results