1 Biosciences Institute, Faculty of Medical Sciences, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, NE4 5PL, UK. Electronic address: viktor.korolchuk@ncl.ac.uk.
2 Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. Electronic address: s.sarkar@bham.ac.uk.
3 Department of Basic and Clinical Neuroscience, King's College London, Maurice Wohl Clinical Neuroscience Institut, London, SE5 9NU, UK. Electronic address: manolis.fanto@kcl.ac.uk.