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Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population.
Thompson EJ, Jeong A, Helfer VE, Shakhnovich V, Edginton A, Balevic SJ, James LP, Collier DN, Anand R, Gonzalez D; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Thompson EJ, et al. CPT Pharmacometrics Syst Pharmacol. 2024 Jun 4. doi: 10.1002/psp4.13167. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38837864
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population.
Maglalang PD, Sinha J, Zimmerman K, McCann S, Edginton A, Hornik CP, Hornik CD, Muller WJ, Al-Uzri A, Meyer M, Chen JY, Anand R, Perrin EM, Gonzalez D; Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. Maglalang PD, et al. Clin Pharmacokinet. 2024 May 30. doi: 10.1007/s40262-024-01367-2. Online ahead of print. Clin Pharmacokinet. 2024. PMID: 38814425
Using Real-World Data to Externally Evaluate Population Pharmacokinetic Models of Dexmedetomidine in Children and Infants.
McCann S, Helfer VE, Balevic SJ, Hornik CD, Goldstein SL, Autmizguine J, Meyer M, Al-Uzri A, Anderson SG, Payne EH, Turdalieva S, Gonzalez D; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. McCann S, et al. Among authors: autmizguine j. J Clin Pharmacol. 2024 Mar 28. doi: 10.1002/jcph.2434. Online ahead of print. J Clin Pharmacol. 2024. PMID: 38545761
Opportunistic dried blood spot sampling validates and optimizes a pediatric population pharmacokinetic model of metronidazole.
Randell RL, Balevic SJ, Greenberg RG, Cohen-Wolkowiez M, Thompson EJ, Venkatachalam S, Smith MJ, Bendel C, Bliss JM, Chaaban H, Chhabra R, Dammann CEL, Downey LC, Hornik C, Hussain N, Laughon MM, Lavery A, Moya F, Saxonhouse M, Sokol GM, Trembath A, Weitkamp J-H, Hornik CP; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Randell RL, et al. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0153323. doi: 10.1128/aac.01533-23. Epub 2024 Mar 14. Antimicrob Agents Chemother. 2024. PMID: 38477706
AMMI Canada Practice Point on the treatment of acute COVID-19 in pediatrics.
Autmizguine J, Barton M, Burton C, Dixit D, Papenburg J, Robinson J, Top KA, Rubin E; AMMI Canada treatment of acute COVID-19 in pediatrics working group. Autmizguine J, et al. J Assoc Med Microbiol Infect Dis Can. 2022 Nov 29;7(4):307-316. doi: 10.3138/jammi-2022-09-20. eCollection 2022 Nov. J Assoc Med Microbiol Infect Dis Can. 2022. PMID: 37397826 Free PMC article. No abstract available.
66 results