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Alternative substitutions of N332 in HIV-1AD8 gp120 differentially affect envelope glycoprotein function and viral sensitivity to broadly neutralizing antibodies targeting the V3-glycan.
Jeffy J, Parthasarathy D, Ahmed S, Cervera-Benet H, Xiong U, Harris M, Mazurov D, Pickthorn S, Herschhorn A. Jeffy J, et al. Among authors: herschhorn a. bioRxiv [Preprint]. 2023 Nov 21:2023.11.20.567910. doi: 10.1101/2023.11.20.567910. bioRxiv. 2023. PMID: 38045336 Free PMC article. Updated. Preprint.
A Protocol for Studying HIV-1 Envelope Glycoprotein Function.
Ratnapriya S, Chov A, Herschhorn A. Ratnapriya S, et al. Among authors: herschhorn a. STAR Protoc. 2020 Oct 14;1(3):100133. doi: 10.1016/j.xpro.2020.100133. eCollection 2020 Dec 18. STAR Protoc. 2020. PMID: 33377027 Free PMC article.
HIV-1 envelope glycoproteins (Envs) bind to CD4 receptor and CCR5/CXCR4 coreceptor and mediate viral entry (Feng et al., 1996; Herschhorn et al., 2016, 2017; Kwong et al., 1998). HIV-1 Envs are the sole target of neutralizing antibodies and a main focus of vaccine d …
HIV-1 envelope glycoproteins (Envs) bind to CD4 receptor and CCR5/CXCR4 coreceptor and mediate viral entry (Feng et al., 1996; Herschhorn …
Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry.
Ratnapriya S, Braun AR, Cervera Benet H, Carlson D, Ding S, Paulson CN, Mishra N, Sachs JN, Aldrich CC, Finzi A, Herschhorn A. Ratnapriya S, et al. Among authors: herschhorn a. ACS Infect Dis. 2022 Oct 14;8(10):2045-2058. doi: 10.1021/acsinfecdis.1c00658. Epub 2022 Sep 26. ACS Infect Dis. 2022. PMID: 36153947 Free PMC article.
Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted / founder sensitivity to broadly neutralizing antibodies.
Parthasarathy D, Pothula KR, Dam KA, Ratnapriya S, Benet HC, Parsons R, Huang X, Sammour S, Janowska K, Harris M, Sacco S, Sodroski J, Bridges MD, Hubbell WL, Acharya P, Herschhorn A. Parthasarathy D, et al. Among authors: herschhorn a. bioRxiv [Preprint]. 2023 Dec 5:2023.09.13.557082. doi: 10.1101/2023.09.13.557082. bioRxiv. 2023. PMID: 37745449 Free PMC article. Preprint.
58 results