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ER stress is involved in T17M rhodopsin-induced retinal degeneration.
Kunte MM, Choudhury S, Manheim JF, Shinde VM, Miura M, Chiodo VA, Hauswirth WW, Gorbatyuk OS, Gorbatyuk MS. Kunte MM, et al. Among authors: gorbatyuk ms, gorbatyuk os. Invest Ophthalmol Vis Sci. 2012 Jun 20;53(7):3792-800. doi: 10.1167/iovs.11-9235. Invest Ophthalmol Vis Sci. 2012. PMID: 22589437 Free PMC article.
The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons.
Salganik M, Sergeyev VG, Shinde V, Meyers CA, Gorbatyuk MS, Lin JH, Zolotukhin S, Gorbatyuk OS. Salganik M, et al. Among authors: gorbatyuk ms, gorbatyuk os. Neurobiol Aging. 2015 Jun;36(6):2213-23. doi: 10.1016/j.neurobiolaging.2015.02.018. Epub 2015 Mar 5. Neurobiol Aging. 2015. PMID: 25863526 Free PMC article.
Unfolded protein response is activated in aged retinas.
Lenox AR, Bhootada Y, Gorbatyuk O, Fullard R, Gorbatyuk M. Lenox AR, et al. Neurosci Lett. 2015 Nov 16;609:30-5. doi: 10.1016/j.neulet.2015.10.019. Epub 2015 Oct 17. Neurosci Lett. 2015. PMID: 26467812 Free PMC article.
51 results