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Function-structure approach reveals novel insights on the interplay of Immunoglobulin G 1 proteoforms and Fc gamma receptor IIa allotypes.
Lippold S, Mistry K, Lenka S, Whang K, Liu P, Pitschi S, Kuhne F, Reusch D, Cadang L, Knaupp A, Izadi S, Dunkle A, Yang F, Schlothauer T. Lippold S, et al. Among authors: izadi s. Front Immunol. 2023 Sep 18;14:1260446. doi: 10.3389/fimmu.2023.1260446. eCollection 2023. Front Immunol. 2023. PMID: 37790943 Free PMC article.
Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.
Wei B, Gao X, Cadang L, Izadi S, Liu P, Zhang HM, Hecht E, Shim J, Magill G, Pabon JR, Dai L, Phung W, Lin E, Wang C, Whang K, Sanchez S, Oropeza J Jr, Camperi J, Zhang J, Sandoval W, Zhang YT, Jiang G. Wei B, et al. Among authors: izadi s. MAbs. 2021 Jan-Dec;13(1):1893427. doi: 10.1080/19420862.2021.1893427. MAbs. 2021. PMID: 33682619 Free PMC article.
Highland games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences.
Coffman J, Marques B, Orozco R, Aswath M, Mohammad H, Zimmermann E, Khouri J, Griesbach J, Izadi S, Williams A, Sankar K, Walters B, Lin J, Hepbildikler S, Schiel J, Welsh J, Ferreira G, Delmar J, Mody N, Afdahl C, Cui T, Khalaf R, Hanke A, Pampel L, Parimal S, Hong X, Patil U, Pollard J, Insaidoo F, Robinson J, Chandra D, Blanco M, Panchal J, Soundararajan S, Roush D, Tugcu N, Cramer S, Haynes C, Willson RC. Coffman J, et al. Among authors: izadi s. Biotechnol Bioeng. 2020 Jul;117(7):2100-2115. doi: 10.1002/bit.27349. Epub 2020 May 9. Biotechnol Bioeng. 2020. PMID: 32255523
214 results