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CAR T cells ignite antitumor immunity.
Alizadeh D, Brown CE. Alizadeh D, et al. Among authors: brown ce. Trends Immunol. 2023 Oct;44(10):748-750. doi: 10.1016/j.it.2023.08.002. Epub 2023 Aug 29. Trends Immunol. 2023. PMID: 37652814
TLR9 is critical for glioma stem cell maintenance and targeting.
Herrmann A, Cherryholmes G, Schroeder A, Phallen J, Alizadeh D, Xin H, Wang T, Lee H, Lahtz C, Swiderski P, Armstrong B, Kowolik C, Gallia GL, Lim M, Brown C, Badie B, Forman S, Kortylewski M, Jove R, Yu H. Herrmann A, et al. Cancer Res. 2014 Sep 15;74(18):5218-28. doi: 10.1158/0008-5472.CAN-14-1151. Epub 2014 Jul 21. Cancer Res. 2014. PMID: 25047528 Free PMC article.
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy.
Brown CE, Alizadeh D, Starr R, Weng L, Wagner JR, Naranjo A, Ostberg JR, Blanchard MS, Kilpatrick J, Simpson J, Kurien A, Priceman SJ, Wang X, Harshbarger TL, D'Apuzzo M, Ressler JA, Jensen MC, Barish ME, Chen M, Portnow J, Forman SJ, Badie B. Brown CE, et al. N Engl J Med. 2016 Dec 29;375(26):2561-9. doi: 10.1056/NEJMoa1610497. N Engl J Med. 2016. PMID: 28029927 Free PMC article. Clinical Trial.
Glioblastoma-targeted CD4+ CAR T cells mediate superior antitumor activity.
Wang D, Aguilar B, Starr R, Alizadeh D, Brito A, Sarkissian A, Ostberg JR, Forman SJ, Brown CE. Wang D, et al. Among authors: brown ce. JCI Insight. 2018 May 17;3(10):e99048. doi: 10.1172/jci.insight.99048. eCollection 2018 May 17. JCI Insight. 2018. PMID: 29769444 Free PMC article.
CAR T cells for brain tumors: Lessons learned and road ahead.
Akhavan D, Alizadeh D, Wang D, Weist MR, Shepphird JK, Brown CE. Akhavan D, et al. Among authors: brown ce. Immunol Rev. 2019 Jul;290(1):60-84. doi: 10.1111/imr.12773. Immunol Rev. 2019. PMID: 31355493 Free PMC article. Review.
Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma.
Wang D, Starr R, Chang WC, Aguilar B, Alizadeh D, Wright SL, Yang X, Brito A, Sarkissian A, Ostberg JR, Li L, Shi Y, Gutova M, Aboody K, Badie B, Forman SJ, Barish ME, Brown CE. Wang D, et al. Among authors: brown ce. Sci Transl Med. 2020 Mar 4;12(533):eaaw2672. doi: 10.1126/scitranslmed.aaw2672. Sci Transl Med. 2020. PMID: 32132216 Free PMC article.
518 results