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Cancers make their own luck: theories of cancer origins.
Jassim A, Rahrmann EP, Simons BD, Gilbertson RJ. Jassim A, et al. Among authors: simons bd. Nat Rev Cancer. 2023 Oct;23(10):710-724. doi: 10.1038/s41568-023-00602-5. Epub 2023 Jul 24. Nat Rev Cancer. 2023. PMID: 37488363 Review.
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms.
Grockowiak E, Korn C, Rak J, Lysenko V, Hallou A, Panvini FM, Williams M, Fielding C, Fang Z, Khatib-Massalha E, García-García A, Li J, Khorshed RA, González-Antón S, Baxter EJ, Kusumbe A, Wilkins BS, Green A, Simons BD, Harrison CN, Green AR, Lo Celso C, Theocharides APA, Méndez-Ferrer S. Grockowiak E, et al. Among authors: simons bd. Nat Cancer. 2023 Aug;4(8):1193-1209. doi: 10.1038/s43018-023-00607-x. Epub 2023 Aug 7. Nat Cancer. 2023. PMID: 37550517 Free PMC article.
Identity and dynamics of mammary stem cells during branching morphogenesis.
Scheele CL, Hannezo E, Muraro MJ, Zomer A, Langedijk NS, van Oudenaarden A, Simons BD, van Rheenen J. Scheele CL, et al. Among authors: simons bd. Nature. 2017 Feb 16;542(7641):313-317. doi: 10.1038/nature21046. Epub 2017 Jan 30. Nature. 2017. PMID: 28135720 Free PMC article.
A single-cell molecular map of mouse gastrulation and early organogenesis.
Pijuan-Sala B, Griffiths JA, Guibentif C, Hiscock TW, Jawaid W, Calero-Nieto FJ, Mulas C, Ibarra-Soria X, Tyser RCV, Ho DLL, Reik W, Srinivas S, Simons BD, Nichols J, Marioni JC, Göttgens B. Pijuan-Sala B, et al. Among authors: simons bd. Nature. 2019 Feb;566(7745):490-495. doi: 10.1038/s41586-019-0933-9. Epub 2019 Feb 20. Nature. 2019. PMID: 30787436 Free PMC article.
Mechanisms of stretch-mediated skin expansion at single-cell resolution.
Aragona M, Sifrim A, Malfait M, Song Y, Van Herck J, Dekoninck S, Gargouri S, Lapouge G, Swedlund B, Dubois C, Baatsen P, Vints K, Han S, Tissir F, Voet T, Simons BD, Blanpain C. Aragona M, et al. Among authors: simons bd. Nature. 2020 Aug;584(7820):268-273. doi: 10.1038/s41586-020-2555-7. Epub 2020 Jul 29. Nature. 2020. PMID: 32728211 Free PMC article.
Tracing oncogene-driven remodelling of the intestinal stem cell niche.
Yum MK, Han S, Fink J, Wu SS, Dabrowska C, Trendafilova T, Mustata R, Chatzeli L, Azzarelli R, Pshenichnaya I, Lee E, England F, Kim JK, Stange DE, Philpott A, Lee JH, Koo BK, Simons BD. Yum MK, et al. Among authors: simons bd. Nature. 2021 Jun;594(7863):442-447. doi: 10.1038/s41586-021-03605-0. Epub 2021 Jun 2. Nature. 2021. PMID: 34079126 Free PMC article.
Retrograde movements determine effective stem cell numbers in the intestine.
Azkanaz M, Corominas-Murtra B, Ellenbroek SIJ, Bruens L, Webb AT, Laskaris D, Oost KC, Lafirenze SJA, Annusver K, Messal HA, Iqbal S, Flanagan DJ, Huels DJ, Rojas-Rodríguez F, Vizoso M, Kasper M, Sansom OJ, Snippert HJ, Liberali P, Simons BD, Katajisto P, Hannezo E, van Rheenen J. Azkanaz M, et al. Among authors: simons bd. Nature. 2022 Jul;607(7919):548-554. doi: 10.1038/s41586-022-04962-0. Epub 2022 Jul 13. Nature. 2022. PMID: 35831497 Free PMC article.
A cellular hierarchy in melanoma uncouples growth and metastasis.
Karras P, Bordeu I, Pozniak J, Nowosad A, Pazzi C, Van Raemdonck N, Landeloos E, Van Herck Y, Pedri D, Bervoets G, Makhzami S, Khoo JH, Pavie B, Lamote J, Marin-Bejar O, Dewaele M, Liang H, Zhang X, Hua Y, Wouters J, Browaeys R, Bergers G, Saeys Y, Bosisio F, van den Oord J, Lambrechts D, Rustgi AK, Bechter O, Blanpain C, Simons BD, Rambow F, Marine JC. Karras P, et al. Among authors: simons bd. Nature. 2022 Oct;610(7930):190-198. doi: 10.1038/s41586-022-05242-7. Epub 2022 Sep 21. Nature. 2022. PMID: 36131018 Free PMC article.
191 results