Margittai M - Search Results

1

MAP2 caps tau fibrils and inhibits aggregation.

Holden MR, Krzesinski BJ, Weismiller HA, Shady JR, Margittai M. Holden MR, et al. Among authors: margittai m. J Biol Chem. 2023 Jul;299(7):104891. doi: 10.1016/j.jbc.2023.104891. Epub 2023 Jun 5. J Biol Chem. 2023. PMID: 37286038 Free PMC article.

2

Fracture and Growth Are Competing Forces Determining the Fate of Conformers in Tau Fibril Populations.

Meyer V, Holden MR, Weismiller HA, Eaton GR, Eaton SS, Margittai M. Meyer V, et al. Among authors: margittai m. J Biol Chem. 2016 Jun 3;291(23):12271-81. doi: 10.1074/jbc.M116.715557. Epub 2016 Apr 14. J Biol Chem. 2016. PMID: 27080260 Free PMC article.

3

Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms.

Weismiller HA, Murphy R, Wei G, Ma B, Nussinov R, Margittai M. Weismiller HA, et al. Among authors: margittai m. J Biol Chem. 2018 Nov 9;293(45):17336-17348. doi: 10.1074/jbc.RA118.005316. Epub 2018 Sep 21. J Biol Chem. 2018. PMID: 30242125 Free PMC article.

4

A thiol-based intramolecular redox switch in four-repeat tau controls fibril assembly and disassembly.

Weismiller HA, Holub TJ, Krzesinski BJ, Margittai M. Weismiller HA, et al. Among authors: margittai m. J Biol Chem. 2021 Sep;297(3):101021. doi: 10.1016/j.jbc.2021.101021. Epub 2021 Jul 31. J Biol Chem. 2021. PMID: 34339733 Free PMC article.

5

RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth.

Dinkel PD, Holden MR, Matin N, Margittai M. Dinkel PD, et al. Among authors: margittai m. Biochemistry. 2015 Aug 4;54(30):4731-40. doi: 10.1021/acs.biochem.5b00453. Epub 2015 Jul 27. Biochemistry. 2015. PMID: 26177386 Free PMC article.

6

Conformational fingerprinting of tau variants and strains by Raman spectroscopy.

Devitt G, Crisford A, Rice W, Weismiller HA, Fan Z, Commins C, Hyman BT, Margittai M, Mahajan S, Mudher A. Devitt G, et al. Among authors: margittai m. RSC Adv. 2021 Feb 26;11(15):8899-8915. doi: 10.1039/d1ra00870f. eCollection 2021. RSC Adv. 2021. PMID: 34381596 Free PMC article.

7

Revealing Conformational Variants of Solution-Phase Intrinsically Disordered Tau Protein at the Single-Molecule Level.

Manger LH, Foote AK, Wood SL, Holden MR, Heylman KD, Margittai M, Goldsmith RH. Manger LH, et al. Among authors: margittai m. Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15584-15588. doi: 10.1002/anie.201708242. Epub 2017 Nov 14. Angew Chem Int Ed Engl. 2017. PMID: 29063723 Free PMC article.

8

Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation.

Foote AK , Manger LH , Holden MR , Margittai M , Goldsmith RH . Foote AK , et al. Among authors: margittai m. Phys Chem Chem Phys. 2019 Jan 23;21(4):1863-1871. doi: 10.1039/c8cp06971a. Phys Chem Chem Phys. 2019. PMID: 30632561 Free PMC article.

9

Driving tau into phase-separated liquid droplets.

Margittai M. Margittai M. J Biol Chem. 2019 Jul 19;294(29):11060-11061. doi: 10.1074/jbc.H119.009703. J Biol Chem. 2019. PMID: 31324714 Free PMC article.

10

Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease.

Siddiqua A, Margittai M. Siddiqua A, et al. Among authors: margittai m. J Biol Chem. 2010 Nov 26;285(48):37920-6. doi: 10.1074/jbc.M110.185728. Epub 2010 Oct 4. J Biol Chem. 2010. PMID: 20921227 Free PMC article.

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