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Fatty acid acylated peptide therapeutics: discovery of omega-n oxidation of the lipid chain as a novel metabolic pathway in preclinical species.
Esposito S, Krick A, Pasquier O, Bonche F, Ingenito R, Magotti P, Bianchi E, Monteagudo E, Gallo M, Cicero DO, Orsatti L, Veneziano M, Caretti F, Mele R, Roversi D, Gennari N, Brasseur D, Gauzy-Lazo L, Duclos O, Mauriac C, Illiano S, Mallart S. Esposito S, et al. Among authors: bianchi e. J Pharm Biomed Anal. 2023 Apr 1;227:115256. doi: 10.1016/j.jpba.2023.115256. Epub 2023 Jan 18. J Pharm Biomed Anal. 2023. PMID: 36764268
Characterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models.
Illiano S, Poirier B, Minoletti C, Pasquier O, Riva L, Chenede X, Menguy I, Guillotel M, Prigent P, Le Claire S, Gillot F, Thill G, Lo Presti F, Corbier A, Le Bail JC, Grailhe P, Monteagudo E, Ingenito R, Bianchi E, Philippo C, Duclos O, Mallart S, Bathgate R, Janiak P. Illiano S, et al. Among authors: bianchi e. Sci Rep. 2022 Nov 28;12(1):20435. doi: 10.1038/s41598-022-24716-2. Sci Rep. 2022. PMID: 36443381 Free PMC article.
R2R01: A long-acting single-chain peptide agonist of RXFP1 for renal and cardiovascular diseases.
Poirier B, Pasquier O, Chenede X, Corbier A, Prigent P, Azam A, Bernard C, Guillotel M, Gillot F, Riva L, Briand V, Ingenito R, Gauzy-Lazo L, Duclos O, Philippo C, Maillere B, Bianchi E, Mallart S, Janiak P, Illiano S. Poirier B, et al. Among authors: bianchi e. Br J Pharmacol. 2024 Jul;181(13):1993-2011. doi: 10.1111/bph.16338. Epub 2024 Mar 7. Br J Pharmacol. 2024. PMID: 38450758
Prospective open-label trial with rituximab in patients with chronic inflammatory demyelinating polyradiculoneuropathy not responding to conventional immune therapies.
Doneddu PE, Cocito D, Fazio R, Benedetti L, Peci E, Liberatore G, Falzone YM, Germano F, Gallia F, Giannotta C, Lleixà C, Bianchi E, Nobile-Orazio E. Doneddu PE, et al. Among authors: bianchi e. J Neurol Neurosurg Psychiatry. 2024 May 10:jnnp-2023-332844. doi: 10.1136/jnnp-2023-332844. Online ahead of print. J Neurol Neurosurg Psychiatry. 2024. PMID: 38729746
877 results