Interleukin 23 receptor: Expression and regulation in immune cells

Eur J Immunol. 2024 Jan;54(1):e2250348. doi: 10.1002/eji.202250348. Epub 2023 Oct 20.

Abstract

The importance of IL-23 and its specific receptor, IL-23R, in the pathogenesis of several chronic inflammatory diseases has been established, but the underlying pathological mechanisms are not fully understood. This review focuses on IL-23R expression and regulation in immune cells.

Keywords: Chronic inflammatory diseases; Gene regulation; Interleukin-23 (IL-23); Interleukin-23 receptor (IL-23R); Transcription factors.

Publication types

  • Review

MeSH terms

  • Interleukin-23 / metabolism
  • Receptors, Interleukin* / genetics
  • Signal Transduction*

Substances

  • Receptors, Interleukin
  • Interleukin-23